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There are 7 ways to get from Mississauga to Pittsburgh by bus, train, car or plane

Select a route below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Map of how to get from Mississauga to Pittsburgh.
Launch map view
  • Distance: 218.8 miles
  • Duration: 10 h 27 min

What companies run services between Mississauga, ON, Canada and Pittsburgh, PA, USA?

You can take a bus from Mississauga to Pittsburgh via Toronto, ON, Buffalo, NY, and Youngstown, OH in around 10 hours 27 minutes. Alternatively, you can take a train from Mississauga to Pittsburgh via Toronto, Buffalo Depew Station Amtrak, and Cleveland Amtrak in around 15 hours 27 minutes.

Airlines
Air Canada
Website
aircanada.com
Flights from Toronto to Pittsburgh
Avg. Duration
1 h 5 min
When
Every day
Estimated price
$150 - $800
Flights from Toronto to Cleveland
Avg. Duration
58 min
When
Every day
Estimated price
$260 - $1,400
Train operators
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Oakville to Buffalo
Avg. Duration
4 h 29 min
Frequency
Every 3 hours
Estimated price
$27 - $80
Website
viarail.ca
Escape
$27 - $40
Economy
$35 - $50
Economy Plus
$55 - $80
Business
$50 - $75
Business Plus/Sleeper
$95 - $140
Train from Toronto to Buffalo
Avg. Duration
5 h 11 min
Frequency
Every 3 hours
Estimated price
$30 - $95
Website
viarail.ca
Escape
$30 - $45
Economy
$40 - $60
Economy Plus
$65 - $95
Business
$60 - $85
Business Plus/Sleeper
$110 - $160
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Buffalo Depew Station Amtrak to Cleveland Amtrak
Avg. Duration
3 h 28 min
Frequency
Twice daily
Estimated price
$40 - $95
Website
amtrak.com
Rome2rio guide to
rome2rio.com
Coach Seat
$40 - $60
Flexi Coach Seat
$70 - $100
Business Coach Seat
$65 - $95
Room
$190 - $270
Train from Cleveland Amtrak to Pittsburgh Amtrak
Avg. Duration
3 h 11 min
Frequency
Once daily
Estimated price
$35 - $85
Website
amtrak.com
Rome2rio guide to
rome2rio.com
Coach Seat
$35 - $55
Flexi Coach Seat
$60 - $90
Business Coach Seat
$55 - $85
Room
$180 - $250
Bus operators
Megabus CA
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Toronto, ON to Buffalo, NY
Avg. Duration
1 h 37 min
Frequency
Once daily
Estimated price
$15 - $40
Website
Greyhound.ca
Advanced Purchase
$15 - $22
Online Fare
$17 - $35
Standard Fare
$26 - $40
Refundable
$30 - $45
Bus from Mississauga, ON to Buffalo, NY
Avg. Duration
2 h 28 min
Frequency
3 times a day
Estimated price
$14 - $40
Website
Greyhound.ca
Advanced Purchase
$14 - $21
Online Fare
$17 - $35
Standard Fare
$26 - $40
Refundable
$30 - $45
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Youngstown, OH to Pittsburgh, PA
Avg. Duration
1 h 22 min
Frequency
Once daily
Estimated price
$13 - $29
Website
greyhound.com
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rome2rio.com
Economy
$13 - $19
Flexible
$23 - $29
Fullington Trailways
Website
fullingtontours.com
Bus from Buffalo, NY to Pittsburgh, PA
Avg. Duration
7 h 40 min
Frequency
Once daily
Estimated price
$50 - $110
Schedules at
fullingtontours.com
Book at
fab.tdstickets.com
Refundable
$70 - $110

How far is it from Mississauga to Pittsburgh?

The distance between Mississauga and Pittsburgh is 350 km. The road distance is 486 km.

What is the cheapest way to get from Mississauga to Pittsburgh?

The cheapest way to get from Mississauga to Pittsburgh is to drive which costs $60 and takes 5 hours 18 minutes.

What is the fastest way to get from Mississauga to Pittsburgh?

The quickest way to get from Mississauga to Pittsburgh is to fly which takes 4 hours 29 minutes and costs $190.

Is there a direct train between Mississauga and Pittsburgh?

No, there is no direct train from Mississauga to Pittsburgh. However, there are services departing from Erindale GO and arriving at Pittsburgh Amtrak via Toronto, Buffalo Depew Station Amtrak and Cleveland Amtrak. The journey, including transfers, takes approximately 15 hours 27 minutes.

Is there a direct bus between Mississauga and Pittsburgh?

No, there is no direct bus from Mississauga to Pittsburgh. However, there are services departing from Mississauga and arriving at Pittsburgh, PA via Toronto, ON, Buffalo, NY and Youngstown, OH. The journey, including transfers, takes approximately 10 hours 27 minutes.

How long does it take to get from Mississauga to Pittsburgh?

It takes approximately 10 hours 27 minutes to get from Mississauga to Pittsburgh, including transfers.