The average bus between Milwaukee and Durham takes 28h 50m and the fastest bus takes 28h. The bus service runs several times per day from Milwaukee to Durham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Milwaukee and Durham. The earliest departure is at 3:25 AM at night, and the last departure from Milwaukee is at 3:20 PM which arrives into Durham at 10:00 PM. All services require a transfer at Chicago Bus Station and take an average of 28h 50m. The schedules shown below are for the next available departures.
Arrives next day


29h • 2 changes
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30h 40m • 2 changes
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29h • 2 changes
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30h 40m • 2 changes
Arrives next day


29h • 2 changes
Arrives next day


30h 40m • 2 changes
Arrives next day


29h • 2 changes
Arrives next day


30h 40m • 2 changes
Want to know about travelling from Milwaukee to Durham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milwaukee to Durham. However, there are services departing from Milwaukee station and arriving at Durham station via Chicago Bus Station station. The journey, including transfers, takes approximately 28h 50m.
Milwaukee to Durham bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
Milwaukee to Durham bus services, operated by Greyhound USA, arrive at Durham station.
Book your Milwaukee to Durham bus tickets online with Greyhound USA and Flixbus USA.
The distance between Milwaukee and Durham is 1,099.1 km. The road distance is 1,727 km.
You can take a bus from Milwaukee Intermodal Station to Durham via Chicago Bus Station and Washington Union Station in around 25h 30m.