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How to get fromMilwaukee to Durhamby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus or train

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There are 7 ways to get from Milwaukee to Durham by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly General Mitchell International Airport to Raleigh-Durham International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Raleigh-Durham International Airport (RDU)planeMKE - RDU
    7h 5m
    $132–783

  2. Train to Chicago Midway International Airport, fly to Raleigh-Durham International Airport

    cheapest
    1. Take the train from Milwaukee to Chicago Union Stationtrain
    2. Fly from Chicago Midway International Airport (MDW) to Raleigh-Durham International Airport (RDU)planeMDW - RDU
    6h 51m
    $104–499

  3. Bus

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
    2. Take the bus from Chicago Bus Station to Washington Union Stationbus
    3. Take the bus from Washington Union Station to Durhambus
    25h 20m
    $131–407

  4. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union StationtrainHiawatha Service / ...
    2. Take the train from Chicago Union Station to CarytrainFloridian
    28h 8m
    $129–1,849

  5. Drive 854.6 mi

    1. Drive from Milwaukee to Durhamcar854.6 mi
    14h 59m
    $156–226

  6. Bus to Chicago O'Hare International Airport, fly to Raleigh-Durham International Airport

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
    2. Fly from Chicago O'Hare International Airport (ORD) to Raleigh-Durham International Airport (RDU)planeORD - RDU
    6h 28m
    $125–431

  7. Fly General Mitchell International Airport to Charlotte Douglas International Airport, train

    1. Fly from General Mitchell International Airport (MKE) to Charlotte Douglas International Airport (CLT)planeMKE - CLT
    2. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain
    8h 24m
    $204–509

Milwaukee to Durham by bus

Calendar14Weekly Buses
Duration25h 20mAverage Duration
Ticket$131Cheapest Price
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Questions & Answers

What companies run services between Milwaukee, WI, USA and Durham, NC, USA?

Southwest Airlines, Delta, and two other airlines fly from General Mitchell International Airport (MKE) to Raleigh-Durham International Airport (RDU) hourly. Alternatively, you can take a bus from Milwaukee Intermodal Station to Durham via Chicago Bus Station and Washington Union Station in around 25h 20m.

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