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How to get fromMilwaukee to Durhamby plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus or train

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There are 8 ways to get from Milwaukee to Durham by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly General Mitchell International Airport to Raleigh-Durham International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Raleigh-Durham International Airport (RDU)plane plane MKE - RDU
    6h 45m
    $122–717

  2. Train to Chicago Midway International Airport, fly to Raleigh-Durham International Airport

    cheapest
    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Raleigh-Durham International Airport (RDU)plane plane MDW - RDU
    6h 56m
    $111–600

  3. Bus

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Durhambus bus
    25h 55m
    $161–327

  4. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train Hiawatha Service / ...
    2. Take the train from Chicago Union Station to Carytrain train Floridian
    28h 8m
    $253–601

  5. Drive 841.4 mi

    1. Drive from Milwaukee to Durhamcar car 841.4 mi
    15h 43m
    $154–222

  6. Bus to Chicago O'Hare International Airport, fly to Raleigh-Durham International Airport

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Raleigh-Durham International Airport (RDU)plane plane ORD - RDU
    6h 25m
    $130–331

  7. Bus to Dane County Regional Airport-Truax Field, fly to Raleigh-Durham International Airport

    1. Take the bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.bus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Raleigh-Durham International Airport (RDU)plane plane MSN - RDU
    7h 17m
    $119–659

  8. Fly General Mitchell International Airport to Charlotte Douglas International Airport, train

    1. Fly from General Mitchell International Airport (MKE) to Charlotte Douglas International Airport (CLT)plane plane MKE - CLT
    2. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain train
    8h 26m
    $136–695

Milwaukee to Durham by bus

Calendar14Weekly Buses
Duration25h 55mAverage Duration
Ticket$161Cheapest Price
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Questions & Answers

What companies run services between Milwaukee, WI, USA and Durham, NC, USA?

Southwest Airlines, Delta, and two other airlines fly from General Mitchell International Airport (MKE) to Raleigh-Durham International Airport (RDU) hourly. Alternatively, you can take a bus from Milwaukee Intermodal Station to Durham via Chicago Bus Station and Washington Union Station in around 25h 55m.

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