There are 8 ways to get from Milwaukee to Durham by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly General Mitchell International Airport to Raleigh-Durham International Airport
best- Fly from General Mitchell International Airport (MKE) to Raleigh-Durham International Airport (RDU)plane MKE - RDU
6h 33m$122–705Train to Chicago Midway International Airport, fly to Raleigh-Durham International Airport
cheapest- Take the train from Milwaukee to Chicago Union Stationtrain
- Fly from Chicago Midway International Airport (MDW) to Raleigh-Durham International Airport (RDU)plane MDW - RDU
6h 52m$111–549Bus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Washington Union Stationbus
- Take the bus from Washington Union Station to Durhambus
25h 25m$152–337Train (Amtrak)
- Take the train from Milwaukee to Chicago Union Stationtrain Hiawatha Service / ...
- Take the train from Chicago Union Station to Carytrain Floridian
28h 37m$324–701Drive 841.4 mi
- Drive from Milwaukee to Durhamcar 841.4 mi
15h 43m$154–222Bus to Chicago O'Hare International Airport, fly to Raleigh-Durham International Airport
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Raleigh-Durham International Airport (RDU)plane ORD - RDU
6h 22m$158–494Bus to Dane County Regional Airport-Truax Field, fly to Raleigh-Durham International Airport
- Take the bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.bus
- Fly from Dane County Regional Airport-Truax Field (MSN) to Raleigh-Durham International Airport (RDU)plane MSN - RDU
7h 6m$122–679Bus to Chicago O'Hare International Airport, fly to Piedmont Triad International Airport, train
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane ORD - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
7h 8m$162–571
Milwaukee to Durham by bus
Questions & Answers
The cheapest way to get from Milwaukee to Durham is to drive which costs $150 - $230 and takes 15h 43m.
The fastest way to get from Milwaukee to Durham is to bus and fly which takes 6h 22m and costs $150 - $500.
No, there is no direct bus from Milwaukee station to Durham. However, there are services departing from Milwaukee Intermodal Station and arriving at Durham via Chicago Bus Station and Washington Union Station. The journey, including transfers, takes approximately 25h 25m.
The distance between Milwaukee and Durham is 717 miles. The road distance is 846.3 miles.
The best way to get from Milwaukee to Durham without a car is to bus which takes 25h 25m and costs $150 - $340.
It takes approximately 6h 33m to get from Milwaukee to Durham, including transfers.
Milwaukee to Durham bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
The best way to get from Milwaukee to Durham is to fly which takes 6h 33m and costs $120 - $750. Alternatively, you can bus, which costs $150 - $340 and takes 25h 25m, you could also train, which costs $320 - $700 and takes 28h 37m.
Milwaukee to Durham bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Durham is 1h ahead of Milwaukee. It is currently 1:03 AM in Milwaukee and 2:03 AM in Durham.
What companies run services between Milwaukee, WI, USA and Durham, NC, USA?
Southwest Airlines, Delta, and two other airlines fly from General Mitchell International Airport (MKE) to Raleigh-Durham International Airport (RDU) hourly. Alternatively, you can take a bus from Milwaukee Intermodal Station to Durham via Chicago Bus Station and Washington Union Station in around 25h 25m.
- Website
- aa.com
Flights from General Mitchell International Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $130–700
Flights from General Mitchell International Airport to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 5h 8m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–750
Flights from General Mitchell International Airport to Raleigh-Durham International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $120–700
Flights from Chicago O'Hare International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 18m
- When
- Every day
- Estimated price
- $60–350
Flights from Dane County Regional Airport-Truax Field to Raleigh-Durham International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $110–650
Flights from Dane County Regional Airport-Truax Field to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 4h 34m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Dane County Regional Airport-Truax Field to Raleigh-Durham International Airport via Philadelphia
- Ave. Duration
- 4h 37m
- When
- Wednesday to Friday
- Estimated price
- $150–750
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $80–460
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport via Charlotte
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $85–490
- Website
- united.com
Flights from General Mitchell International Airport to Raleigh-Durham International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $120–700
Flights from Chicago O'Hare International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 16m
- When
- Every day
- Estimated price
- $60–350
Flights from Dane County Regional Airport-Truax Field to Raleigh-Durham International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $110–650
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport
- Ave. Duration
- 2h 4m
- When
- Every day
- Estimated price
- $80–460
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $100–550
- Website
- southwest.com
Flights from General Mitchell International Airport to Raleigh-Durham International Airport via Chicago Midway International Airport
- Ave. Duration
- 3h 42m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $120–700
Flights from General Mitchell International Airport to Raleigh-Durham International Airport via St. Louis
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $150–800
Flights from General Mitchell International Airport to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 5h 8m
- When
- Monday to Saturday
- Estimated price
- $140–750
Flights from General Mitchell International Airport to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 5h 12m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $140–750
Flights from Chicago Midway International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $85–490
- Website
- delta.com
Flights from General Mitchell International Airport to Raleigh-Durham International Airport via Detroit
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $120–700
Flights from Dane County Regional Airport-Truax Field to Raleigh-Durham International Airport via Detroit
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $120–650
Flights from Dane County Regional Airport-Truax Field to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $150–750
Flights from Dane County Regional Airport-Truax Field to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 5h 8m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–700
Flights from Chicago Midway International Airport to Raleigh-Durham International Airport via Detroit
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $95–550
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $110–550
- Website
- flybreeze.com
Flights from Dane County Regional Airport-Truax Field to Raleigh-Durham International Airport
- Ave. Duration
- 2h 10m
- When
- Monday and Friday
- Estimated price
- $190–1,500
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $23–55
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Cary
- Ave. Duration
- 24h 21m
- Frequency
- Once daily
- Estimated price
- $300–650
- Website
- https://www.amtrak.com/home.html
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $15–35
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $14–28
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Washington Union Station
- Ave. Duration
- 16h 35m
- Frequency
- Twice daily
- Estimated price
- $110–230
- Website
- https://www.greyhound.com/
Bus from Washington Union Station to Durham
- Ave. Duration
- 6h 40m
- Frequency
- 3 times a day
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
Bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $12–25
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 3 times a day
- Estimated price
- $11–20
- Schedules at
- flixbus.com
Bus from Washington Union Station to Durham
- Ave. Duration
- 5h 5m
- Frequency
- 4 times a day
- Estimated price
- $30–60
- Schedules at
- flixbus.com
Bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $10–18
- Schedules at
- flixbus.com
- Phone
- (866) 912 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- https://www.coachusa.com/wisconsin-coach?gad_source=1&gclid=CjwKCAiAt4C-BhBcEiwA8Kp0Cc3RRg_kOdc3CzsoiFSe4BX-r10-kIOeuDNMfsAKsG5uubvoAmxcrRoC5LwQAvD_BwE
- Phone
- +1 414-266-4409
- ticketinfo@badgerbus.com
- Website
- badgerbus.com
Bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.
- Ave. Duration
- 1h 35m
- Frequency
- 5 times a day
- Estimated price
- $23–30
- Website
- https://badgerbus.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.
- Ave. Duration
- 1h 15m
- Frequency
- Twice daily
- Estimated price
- $29–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $29–40
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More Questions & Answers
Yes, the driving distance between Milwaukee to Durham is 846 miles. It takes approximately 15h 43m to drive from Milwaukee to Durham.
Book your Milwaukee to Durham bus tickets online with Omio and FlixBus.
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