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How to get fromMilwaukee to Durhamby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train

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There are 9 ways to get from Milwaukee to Durham by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly General Mitchell International Airport to Raleigh-Durham International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Raleigh-Durham International Airport (RDU)plane plane MKE - RDU
    6h 28m
    $128–658

  2. Bus

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Durhambus bus
    25h 49m
    $153–320

  3. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train Hiawatha Service / ...
    2. Take the train from Chicago Union Station to Carytrain train Floridian
    28h 42m
    $363–812

  4. Drive 841.3 mi

    1. Drive from Milwaukee to Durhamcar car 841.3 mi
    15h 45m
    $154–222

  5. Bus to Chicago O'Hare International Airport, fly to Raleigh-Durham International Airport

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Raleigh-Durham International Airport (RDU)plane plane ORD - RDU
    6h 20m
    $214–797

  6. Train to Chicago Midway International Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Raleigh-Durham International Airport (RDU)plane plane MDW - RDU
    6h 40m
    $188–370

  7. Bus to Dane County Regional Airport-Truax Field, fly to Raleigh-Durham International Airport

    1. Take the bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.bus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Raleigh-Durham International Airport (RDU)plane plane MSN - RDU
    7h 9m
    $151–698

  8. Bus to Chicago O'Hare International Airport, fly to Piedmont Triad International Airport, train

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane plane ORD - GSO
    3. Take the train from Greensboro to Durham Amtrak Stationtrain train
    7h 7m
    $184–716

  9. Fly General Mitchell International Airport to Charlotte Douglas International Airport, train

    1. Fly from General Mitchell International Airport (MKE) to Charlotte Douglas International Airport (CLT)plane plane MKE - CLT
    2. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain train
    8h 17m
    $201–908

Milwaukee to Durham by bus

Calendar28Weekly Buses
Duration25h 49mAverage Duration
Ticket$153Cheapest Price
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Questions & Answers

Map of how to get from Milwaukee to Durham.ExpandLaunch map view
  • Distance: 712.8 mi
  • Duration: 6h 28m

What companies run services between Milwaukee, WI, USA and Durham, NC, USA?

Southwest Airlines, American Airlines, and two other airlines fly from General Mitchell International Airport (MKE) to Raleigh-Durham International Airport (RDU) hourly. Alternatively, you can take a bus from Milwaukee Intermodal Station to Durham via Chicago Bus Station and Washington Union Station in around 25h 49m.

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