The average bus between Milan and Pienza takes 9h 51m and the fastest bus takes 7h 24m. The bus service runs several times per day from Milan to Pienza. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Milan and Pienza. The earliest departure is at 1:10 AM at night, and the last departure from Milan is at 2:45 PM which arrives into Pienza at 7:29 AM. All services require a transfer at Siena and take an average of 9h 51m. The schedules shown below are for the next available departures.


7h 24m • 2 changes


7h 34m • 2 changes


8h 19m • 2 changes
Arrives next day


16h 44m • 2 changes


7h 24m • 2 changes


8h 19m • 2 changes
Arrives next day


17h 4m • 2 changes
Want to know about travelling from Milan to Pienza? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milan to Pienza. However, there are services departing from Milan station and arriving at Pienza station via Siena. The journey, including transfers, takes approximately 9h 51m.
Milan to Pienza bus services, operated by FlixBus, depart from Milano, San Donato M3 station.
Milan to Pienza bus services, operated by FlixBus, arrive at Siena station.
The distance between Milan and Pienza is 331.3 km. The road distance is 416 km.
FlixBus operates a bus from Milano, San Donato M3 to Siena 5 times a day. Tickets cost €25–45 and the journey takes 4h 20m.