The average bus between Messina and Comiso takes 7h 32m and the fastest bus takes 6h 20m. The bus service runs several times per day from Messina to Comiso. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Messina and Comiso. The earliest departure is at 6:35 AM in the morning, and the last departure from Messina is at 8:55 PM which arrives into Comiso at 5:55 AM. All services require a transfer at Catania and take an average of 7h 32m. The schedules shown below are for the next available departures.


6h 20m • 2 changes


7h • 2 changes
Arrives next day


10h • 2 changes


6h 20m • 2 changes


7h • 2 changes
Arrives next day


10h • 2 changes


6h 20m • 2 changes


7h • 2 changes
Arrives next day


10h • 2 changes
Want to know about travelling from Messina to Comiso? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Messina to Comiso. However, there are services departing from Messina station and arriving at Comiso station via Catania. The journey, including transfers, takes approximately 7h 32m.
Messina to Comiso bus services, operated by FlixBus, depart from Messina station.
Messina to Comiso bus services, operated by FlixBus, arrive at Ragusa Bus Terminal station.
The distance between Messina and Comiso is 161.6 km. The road distance is 210 km.
You can take a bus from Messina to Comiso via Catania, Catania Via Archimede, and Ragusa in around 5h 28m.