The average bus between Messina and Perugia takes 13h 55m and the fastest bus takes 12h 15m. The bus service runs several times per day from Messina to Perugia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Messina and Perugia. The earliest departure is at 12:50 AM at night, and the last departure from Messina is at 9:30 PM which arrives into Perugia at 9:45 AM. All services require a transfer, and take on average 13h 55m. The schedules shown below are for the next available departures.
Arrives next day

15h 5m • 1 change
Arrives next day

12h 15m • 1 change

14h 25m • 1 change
Arrives next day

15h 5m • 1 change
Arrives next day

12h 15m • 1 change

14h 25m • 1 change
Arrives next day

15h 5m • 1 change
Arrives next day

12h 15m • 1 change

14h 25m • 1 change
Arrives next day

15h 5m • 1 change
Arrives next day

12h 15m • 1 change

14h 25m • 1 change
Arrives next day

15h 5m • 1 change
Arrives next day

12h 15m • 1 change
Want to know about travelling from Messina to Perugia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Messina to Perugia. However, there are services departing from Messina station and arriving at Perugia station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 13h 55m.
Messina to Perugia bus services, operated by FlixBus, depart from Messina station.
Messina to Perugia bus services, operated by FlixBus, arrive at Perugia station.
Book your Messina to Perugia bus tickets online with FlixBus.
The distance between Messina and Perugia is 608.4 km. The road distance is 878 km.
You can take a bus from Messina to Perugia via Roma, Autostazione Tiburtina in around 12h 40m.