The average bus between Mannheim and Messina takes 31h 50m and the fastest bus takes 28h 20m. The bus service runs several times per day from Mannheim to Messina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Mannheim and Messina. The earliest departure is at 12:00 AM at night, and the last departure from Mannheim is at 6:30 AM which arrives into Messina at 7:50 PM. All services require a transfer, and take on average 31h 50m. The schedules shown below are for the next available departures.
Arrives next day

30h 20m • 1 change
Arrives next day

37h 20m • 1 change
Arrives next day

30h 20m • 1 change
Arrives next day

37h 20m • 1 change
Arrives next day

30h 20m • 1 change
Arrives next day

37h 20m • 1 change
Arrives next day

30h 20m • 1 change
Arrives next day

37h 20m • 1 change
Want to know about travelling from Mannheim to Messina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mannheim to Messina. However, there are services departing from Mannheim station and arriving at Messina station via Milan. The journey, including transfers, takes approximately 31h 50m.
Mannheim to Messina bus services, operated by FlixBus, depart from Mannheim central bus station.
Mannheim to Messina bus services, operated by FlixBus, arrive at Messina station.
Book your Mannheim to Messina bus tickets online with FlixBus.
The distance between Mannheim and Messina is 1,377 km. The road distance is 1,877 km.
You can take a bus from Mannheim central bus station to Messina via Milano, Autostazione Lampugnano in around 26h 35m.