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Manchester to Southwark buses

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Trip Overview

The average bus between Manchester and Southwark takes 5h 44m and the fastest bus takes 4h 33m. There is a bus service every few hours from Manchester to Southwark. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 44m
Duration
204 mi
Distance
£32
Average price
Hourly
Frequency

Bus via Finchley Road / O2 Centre

best
  1. Take the bus from Shudehill Interchange to Finchley Road / O2 Centrebus bus Ukn30 / ...
4h 51m
£28–39

Manchester to Southwark bus times

Buses run hourly between Manchester and Southwark. The earliest departure is at 2:45 AM at night, and the last departure from Manchester is at 7:30 PM which arrives into Southwark at 12:10 AM. All services require a transfer at Finchley Road / O2 Centre and take an average of 5h 44m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

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    Arrives next day

    National ExpressFirst Bus London4h 40m • 1 change

Departing Thursday, November 5, 2026

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    National ExpressFirst Bus London6h 23m • 1 change

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    National ExpressFirst Bus London5h 29m • 1 change

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    National ExpressFirst Bus London6h 23m • 1 change

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    National ExpressFirst Bus London6h 10m • 1 change
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Departing Friday, November 6, 2026

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    National ExpressFirst Bus London6h 23m • 1 change

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    National ExpressFirst Bus London5h 28m • 1 change

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    National ExpressFirst Bus London5h 23m • 1 change

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    National ExpressFirst Bus London6h 18m • 1 change
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Departing Saturday, November 7, 2026

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    National ExpressFirst Bus London6h 8m • 1 change

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    National ExpressFirst Bus London5h 10m • 1 change

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    National ExpressFirst Bus London5h 53m • 1 change

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    National ExpressFirst Bus London5h 15m • 1 change
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Departing Sunday, November 8, 2026

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    National ExpressFirst Bus London5h 58m • 1 change

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    National ExpressFirst Bus London5h 9m • 1 change

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    National ExpressFirst Bus London5h 52m • 1 change

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    National ExpressFirst Bus London5h 14m • 1 change
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Departing Monday, November 9, 2026

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    National ExpressFirst Bus London6h 23m • 1 change

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    National ExpressFirst Bus London5h 29m • 1 change

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    National ExpressFirst Bus London6h 23m • 1 change

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    National ExpressFirst Bus London6h 10m • 1 change
  • Show more

Departing Tuesday, November 10, 2026

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    National ExpressFirst Bus London6h 23m • 1 change

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    National ExpressFirst Bus London5h 29m • 1 change

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    National ExpressFirst Bus London6h 23m • 1 change

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    National ExpressFirst Bus London6h 10m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Manchester to Southwark? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Manchester to Southwark.ExpandLaunch map view
  • Distance: 204.3 mi
  • Duration: 5h 44m

What companies run services between Manchester, England and Southwark, England?

FlixBus operates a bus from Shudehill Interchange to Finchley Road / O2 Centre hourly. Tickets cost £23–35 and the journey takes 4h 35m.

Operators