The average bus between Manchester and Luton takes 4h 29m and the fastest bus takes 3h 35m. There is a bus service every few hours from Manchester to Luton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Manchester and Luton. The earliest departure is at 2:45 AM at night, and the last departure from Manchester is at 11:40 PM which arrives into Luton at 5:45 AM. All services require a transfer, and take on average 4h 29m. The schedules shown below are for the next available departures.

5h 10m • 1 change

3h 45m • 1 change

3h 50m • 1 change

3h 40m • 1 change

5h 10m • 1 change

3h 45m • 1 change

3h 50m • 1 change

3h 40m • 1 change

5h 10m • 1 change

3h 45m • 1 change

3h 50m • 1 change

3h 40m • 1 change

5h 10m • 1 change

4h 10m • 1 change

3h 55m • 1 change

3h 45m • 1 change
Want to know about travelling from Manchester to Luton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Luton. However, there are services departing from Manchester station and arriving at Luton station via Milton Keynes Coachway. The journey, including transfers, takes approximately 4h 29m.
Manchester to Luton bus services, operated by National Express, depart from Manchester Central Coach Station.
Manchester to Luton bus services, operated by National Express, arrive at Milton Keynes Coachway station.
Book your Manchester to Luton bus tickets online with National Express.
The distance between Manchester and Luton is 216.2 km. The road distance is 250 km.
National Express operates a bus from Manchester Central Coach Station to Milton Keynes Coachway hourly. Tickets cost £25–65 and the journey takes 2h 55m.