The average train between Manchester and Luton takes 2h 51m and the fastest train takes 2h 34m. The train runs at least 2 times per hour from Manchester to Luton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 30 minutes between Manchester and Luton. The earliest departure is at 5:05 AM in the morning, and the last departure from Manchester is at 10:15 PM which arrives into Luton at 2:33 AM. All services require a transfer at London Euston and take an average of 2h 51m. The schedules shown below are for the next available departures.

2h 34m • 1 change

3h 1m • 1 change

2h 54m • 1 change

3h 1m • 1 change

3h 4m • 1 change

3h 1m • 1 change

2h 44m • 1 change

2h 34m • 1 change

3h 37m • 1 change

3h 36m • 1 change

3h 35m • 1 change

3h 1m • 1 change
Want to know about travelling from Manchester to Luton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manchester to Luton. However, there are services departing from Manchester station and arriving at Luton station via London Euston. The journey, including transfers, takes approximately 2h 51m.
Manchester to Luton train services, operated by Avanti West Coast, depart from Manchester Piccadilly station.
Manchester to Luton train services, operated by Avanti West Coast, arrive at Luton station.
Book your Manchester to Luton train tickets online with Avanti West Coast, East Midlands Railways and Thameslink.
The distance between Manchester and Luton is 216.2 km. The road distance is 343 km.
You can take a train from Manchester Piccadilly to Luton via London Euston and London St Pancras Intl in around 2h 57m.