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Mainz to Lisse buses

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Trip Overview

The average bus between Mainz and Lisse takes 12h 5m and the fastest bus takes 9h 15m. The bus service runs several times per day from Mainz to Lisse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 5m
Duration
536 km
Distance
€65
Average price
3 times a day
Frequency

Mainz to Lisse bus times

Buses run 3 times a day between Mainz and Lisse. The earliest departure is at 3:55 AM at night, and the last departure from Mainz is at 10:30 PM which arrives into Lisse at 9:39 AM. All services require a transfer at Frankfurt central train station and take an average of 12h 5m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

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    Arrives next day

    FlixBusFlixBusGVBQbuzz B.V.11h 9m • 3 changes

Departing Saturday, November 7, 2026

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    FlixBusFlixBusGVBQbuzz B.V.9h 44m • 3 changes
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    FlixBusFlixBusGVBQbuzz B.V.10h 29m • 3 changes
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    Arrives next day

    FlixBusFlixBusGVBQbuzz B.V.14h 4m • 3 changes
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    Arrives next day

    FlixBusFlixBusGVBQbuzz B.V.11h 11m • 3 changes

Departing Sunday, November 8, 2026

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    FlixBusFlixBusGVBQbuzz B.V.10h 31m • 3 changes
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    Arrives next day

    FlixBusFlixBusGVBQbuzz B.V.13h 50m • 3 changes
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    Arrives next day

    FlixBusFlixBusGVBQbuzz B.V.10h 40m • 3 changes

Departing Monday, November 9, 2026

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    FlixBusFlixBusGVBQbuzz B.V.10h 30m • 3 changes
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    Arrives next day

    FlixBusFlixBusGVBQbuzz B.V.10h 40m • 3 changes

Departing Tuesday, November 10, 2026

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    FlixBusFlixBusGVBQbuzz B.V.9h 15m • 3 changes
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    FlixBusFlixBusGVBQbuzz B.V.15h 6m • 3 changes
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    Arrives next day

    FlixBusFlixBusGVBQbuzz B.V.13h 50m • 3 changes
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    Arrives next day

    FlixBusFlixBusGVBQbuzz B.V.13h 10m • 3 changes

Departing Wednesday, November 11, 2026

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    FlixBusFlixBusGVBQbuzz B.V.14h 31m • 3 changes
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    Arrives next day

    FlixBusFlixBusGVBQbuzz B.V.13h 10m • 3 changes

Departing Thursday, November 12, 2026

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    FlixBusFlixBusGVBQbuzz B.V.9h 15m • 3 changes
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    FlixBusFlixBusGVBQbuzz B.V.14h 31m • 3 changes

Frequently asked questions

Want to know about travelling from Mainz to Lisse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mainz to Lisse.ExpandLaunch map view
  • Distance: 536 km
  • Duration: 12h 5m

What companies run services between Mainz, Germany and Lisse, Netherlands?

FlixBus operates a bus from Frankfurt central train station to Amsterdam Sloterdijk hourly. Tickets cost €40–60 and the journey takes 6h 10m.

Operators