Rome2Rio

Madrid to Messina buses

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Trip Overview

The bus between Madrid and Messina takes 2d. The bus runs, on average, 6 times per week from Madrid to Messina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d
Duration
2,931 km
Distance
€314
Average price
6 times a week
Frequency

Madrid to Messina bus times

Buses run 6 times a week between Madrid and Messina. The service departs Madrid at 6:05 PM in the evening, which arrives into Messina at 19:50:00. All services require a transfer, and take on average 2d. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus2d • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus2d • 1 change

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus2d • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus2d • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus2d • 1 change

Departing Monday, November 16, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus2d • 1 change

Frequently asked questions

Want to know about travelling from Madrid to Messina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid to Messina.ExpandLaunch map view
  • Distance: 2,931.5 km
  • Duration: 2d

What companies run services between Madrid, Spain and Messina, Italy?

You can take a bus from Madrid to Messina via Milano, Autostazione Lampugnano in around 41h 20m.

Operators