The average bus between Lyon and Santander takes 16h 9m and the fastest bus takes 14h 30m. The bus service runs several times per day from Lyon to Santander. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Lyon and Santander. The earliest departure is at 1:15 PM in the afternoon, and the last departure from Lyon is at 8:05 PM which arrives into Santander at 4:50 PM. All services require a transfer, and take on average 16h 9m. The schedules shown below are for the next available departures.
Arrives next day

15h 30m • 1 change
Arrives next day

16h 40m • 1 change
Arrives next day

19h 55m • 1 change
Arrives next day

18h 45m • 1 change
Arrives next day

16h 40m • 1 change
Arrives next day

18h 45m • 1 change
Arrives next day

16h 40m • 1 change
Arrives next day

19h 55m • 1 change
Want to know about travelling from Lyon to Santander? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lyon to Santander. However, there are services departing from Lyon station and arriving at Santander station via Bilbao. The journey, including transfers, takes approximately 16h 9m.
Lyon to Santander bus services, operated by BlaBlaCar Bus, depart from Lyon - Gerland Bus Station.
Lyon to Santander bus services, operated by BlaBlaCar Bus, arrive at Santander E.A. station.
Book your Lyon to Santander bus tickets online with BlaBlaCar Bus, ALSA and FlixBus.
The distance between Lyon and Santander is 730 km. The road distance is 963 km.
You can take a bus from Lyon - Gerland Bus Station to Santander E.A. via Bilbao Intermodal in around 14h.