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How to get fromLyon to Santanderby plane, train (Renfe, Ouigo), bus, car, or train

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There are 8 ways to get from Lyon to Santander by plane, train (Renfe, Ouigo), bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Santander Airport

    best
    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Santander Airport (SDR)plane plane LYS - SDR
    6h 55m
    €101–336

  2. Bus

    cheapest
    1. Take the bus from Lyon - Gerland Bus Station to Bilbao Intermodalbus bus BlaBlaCar Bus
    2. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus ALSA - Bilb-Stder / ...
    13h 58m
    €73–119

  3. Train

    1. Take the train from Lyon Part Dieu to Barcelona-Santstrain train
    2. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train Ave
    3. Take the train from Madrid Chamartín to Santandertrain train Alv / ...
    13h 16m
    €184–350

  4. Drive  954.2 km

    1. Drive from Lyon to Santandercar car 954.2 km
    9h 31m
    €156–225

  5. Fly to Bilbao Airport, bus

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Bilbao Airport (BIO)plane plane LYS - BIO
    2. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    9h 9m
    €90–242

  6. Fly to Biarritz Pays Basque Airport, bus

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Biarritz Pays Basque Airport (BIQ)plane plane LYS - BIQ
    2. Take the bus from Biarritz - Airport Bus Station to Bilbao Intermodalbus bus
    3. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    8h 19m
    €110–358

  7. Train, bus

    1. Take the train from Lyon Part Dieu to Toulouse Matabiautrain train Tgv
    2. Take the train from Toulouse Matabiau to Bayonnetrain train
    3. Take the bus from Bayonne to Bilbaobus bus
    4. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    13h 58m
    €189–294

  8. Bus via Bilbao

    1. Take the bus from Lyon to Bilbaobus bus FlixBus N1149 / ...
    2. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus ALSA - Bilb-Stder / ...
    14h 33m
    €85–125

Lyon to Santander by train

Calendar14Weekly Trains
Duration13h 16mAverage Duration
Ticket€184Cheapest Price
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Map of how to get from Lyon to Santander.ExpandLaunch map view
  • Distance: 770.7 km
  • Duration: 6h 55m

What companies run services between Lyon, France and Santander, Spain?

Vueling Airlines, Iberia, and easyJet fly from Lyon–Saint Exupéry Airport (LYS) to Santander Airport (SDR) 3 times a day. Alternatively, you can take a train from Lyon Part Dieu to Santander via Barcelona-Sants, Madrid-Puerta De Atocha-Almudena Grandes, Madrid-Atocha Cercanías, and Madrid Chamartín in around 13h 16m.

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