The average bus between Lyon and Opio takes 10h 16m and the fastest bus takes 7h 22m. The bus service runs several times per day from Lyon to Opio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Lyon and Opio. The earliest departure is at 2:35 AM at night, and the last departure from Lyon is at 11:45 AM which arrives into Opio at 6:36 AM. All services require a transfer at Pôle d'Echanges and take an average of 10h 16m. The schedules shown below are for the next available departures.


7h 27m • 2 changes


7h 52m • 2 changes
Arrives next day


18h 51m • 2 changes


7h 27m • 2 changes


7h 52m • 2 changes
Arrives next day


19h 49m • 2 changes


8h 10m • 2 changes


7h 22m • 2 changes
Arrives next day


19h 49m • 2 changes
Want to know about travelling from Lyon to Opio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lyon to Opio. However, there are services departing from Lyon station and arriving at Opio station via Antibes. The journey, including transfers, takes approximately 10h 16m.
Lyon to Opio bus services, operated by FlixBus, depart from Lyon station.
Lyon to Opio bus services, operated by FlixBus, arrive at Antibes station.
The distance between Lyon and Opio is 286.3 km. The road distance is 533 km.
FlixBus operates a bus from Lyon to Antibes twice daily. Tickets cost €40–75 and the journey takes 6h 10m.