Rome2Rio

Lyon to Brussels buses

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Trip Overview

The bus between Lyon and Brussels takes 10h 20m. The bus runs, on average, 2 times per week from Lyon to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 20m
Duration
786 km
Distance
€85
Average price
Twice a week
Frequency

Lyon to Brussels bus times

Buses run twice a week between Lyon and Brussels. The service departs Lyon at 1:25 AM at night, which arrives into Brussels at 11:45:00. All services run direct with no transfers required, and take on average 10h 20m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    bus bus 10h 20m • Direct

Departing Monday, November 16, 2026

  •  → 

    bus bus 10h 20m • Direct

Frequently asked questions

Want to know about travelling from Lyon to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Lyon to Brussels.ExpandLaunch map view
  • Distance: 786.5 km
  • Duration: 10h 20m

What companies run services between Lyon, France and Brussels, Belgium?

FlixBus operates a bus from Lyon to Brussels-North train station twice a week. Tickets cost €70–110 and the journey takes 10h 20m.

Operators