• Our partners include:

  • RailEurope
  • Deutsche Bahn
  • Trenitalia
  • SNCF
  • Flixbus
  • RENFE
  • Ouibus
  • BlaBlaCar
  • Booking.com
  • Skyscanner

There are 8 ways to get from Lyon to Brussels by train, bus, rideshare, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  3h 43m

  1. Take the train from Lyon Part Dieu to Bruxelles Midi Tgv

$140 - $160

Cheapest option

Bus  •  11h 10m

  1. Take the bus from Lyon, Lyon Perrache to Brussels, Brussels-North station N769

$45 - $140

6 alternative options

Rideshare  •  8h 31m

  1. Take the rideshare from Lyon to Brussels 474.9 miles

$54 - $56

Drive  •  6h 55m

  1. Drive from Lyon to Brussels 455.5 miles

$95 - $150

Fly Lyon to Brussels  •  4h 12m

  1. Fly from Lyon (LYS) to Brussels (BRU) LYS - BRU

$50 - $238

Train to Geneva, fly to Brussels  •  5h 54m

  1. Take the train from Gare de Lyon-Part-Dieu to Gare de Genève
  2. Fly from Geneva (GVA) to Brussels (BRU) GVA - BRU

$77 - $250

Fly Lyon to Lille Lesquin, train  •  5h 22m

  1. Fly from Lyon (LYS) to Lille Lesquin (LIL) LYS - LIL
  2. Take the train from Lille Europe Eurostar to Bruxelles-Midi Eurostar

$106 - $367

Fly Lyon to Paris CDG, train  •  5h 15m

  1. Fly from Lyon (LYS) to Paris CDG (CDG) LYS - CDG
  2. Take the train from Aeroport Paris-Charles de Gaulle TGV to Bruxelles Midi

$101 - $377

Questions & Answers

The cheapest way to get from Lyon to Brussels is to rideshare which costs 47€ - 48€ and takes 8h 31m.

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The quickest way to get from Lyon to Brussels is to train which costs 120€ - 140€ and takes 3h 43m.

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Yes, there is a direct bus departing from Lyon, Lyon Perrache and arriving at Brussels, Brussels-North station station. Services depart twice daily, and operate every day. The journey takes approximately 11h 10m.

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Yes, there is a direct train departing from Lyon Part Dieu and arriving at Bruxelles Midi. Services depart four times a day, and operate every day. The journey takes approximately 3h 43m.

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The distance between Lyon and Brussels is 569 km. The road distance is 728.8 km.

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The best way to get from Lyon to Brussels without a car is to train which takes 3h 43m and costs 120€ - 140€.

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The train from Lyon Part Dieu to Bruxelles Midi takes 3h 43m including transfers and departs four times a day.

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Lyon to Brussels bus services, operated by FlixBus, depart from Lyon, Lyon Perrache station.

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Lyon to Brussels train services, operated by inOui TGV, depart from Lyon Part Dieu station.

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The best way to get from Lyon to Brussels is to train which takes 3h 43m and costs 120€ - 140€. Alternatively, you can bus, which costs 35€ - 120€ and takes 11h 10m, you could also fly, which costs 40€ - 210€ and takes 4h 12m.

Mode details

Map of how to get from Lyon to Brussels.
Launch map view
  • Distance: 355.3 miles
  • Duration: 3h 43m

What companies run services between Lyon, France and Brussels, Belgium?

inOui TGV operates a train from Lyon to Brussels 4 times a day. Tickets cost $140 - $160 and the journey takes 3h 43m. Alternatively, FlixBus operates a bus from Lyon to Brussels twice daily. Tickets cost $45 - $75 and the journey takes 11h 10m. Eurolines FR also services this route twice daily.

Airlines
Air France
Website
airfrance.com
Flights from Lyon to Brussels
Ave. Duration
1h 23m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $420
Flights from Lyon to Brussels via Amsterdam Schiphol
Ave. Duration
3h 20m
When
Monday to Saturday
Estimated price
$140 - $550
Flights from Lyon to Lille Lesquin
Ave. Duration
1h 15m
When
Every day
Estimated price
$100 - $450
Flights from Lyon to Lille Lesquin via Nantes
Ave. Duration
3h 15m
When
Monday to Friday
Estimated price
$100 - $450
Flights from Lyon to Paris CDG
Ave. Duration
1h 12m
When
Every day
Estimated price
$50 - $310
Brussels Airlines
Website
brusselsairlines.com
Flights from Lyon to Brussels
Ave. Duration
1h 21m
When
Every day
Estimated price
$60 - $370
Flights from Geneva to Brussels
Ave. Duration
1h 17m
When
Every day
Estimated price
$60 - $460
Flights from Lyon to Paris CDG via Brussels
Ave. Duration
3h 20m
When
Monday to Saturday
Estimated price
$430 - $1,300
Swiss
Website
swiss.com
Flights from Geneva to Brussels
Ave. Duration
1h 17m
When
Every day
Estimated price
$60 - $460
Flights from Geneva to Brussels via Zurich
Ave. Duration
3h 15m
When
Every day
Estimated price
$110 - $400
Hop!
Website
hop.com
Flights from Lyon to Brussels
Ave. Duration
1h 23m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $430
Flights from Lyon to Lille Lesquin
Ave. Duration
1h 15m
When
Every day
Estimated price
$100 - $450
Flights from Lyon to Lille Lesquin via Nantes
Ave. Duration
3h 15m
When
Monday to Friday
Estimated price
$100 - $450
Lufthansa
Website
lufthansa.com
Flights from Lyon to Brussels via Frankfurt
Ave. Duration
3h 37m
When
Every day
Estimated price
$160 - $600
Flights from Geneva to Brussels via Frankfurt
Ave. Duration
3h 17m
When
Every day
Estimated price
$150 - $650
Flights from Geneva to Brussels via Munich
Ave. Duration
3h 30m
When
Every day
Estimated price
$150 - $650
easyJet
Website
easyjet.com
Flights from Geneva to Brussels
Ave. Duration
1h 18m
When
Every day
Estimated price
$45 - $290
XL Airways France
Website
xl.com
Flights from Lyon to Paris CDG
Ave. Duration
1h 20m
When
Thursday and Friday
Estimated price
$30 - $140
KLM
Website
klm.com
Flights from Lyon to Brussels via Amsterdam Schiphol
Ave. Duration
3h 20m
When
Monday to Saturday
Estimated price
$140 - $550
Train operators
inOui TGV
Phone
0033 892 353535
Website
en.oui.sncf
Train from Lyon Part Dieu to Bruxelles Midi
Ave. Duration
3h 43m
Frequency
4 times a day
Estimated price
$140 - $160
Website
en.oui.sncf
2nd Class
$140 - $160
1st Class
$190 - $280
Train from Lyon Part Dieu to Genève
Ave. Duration
1h 44m
Frequency
3 times a week
Estimated price
$35 - $45
Website
en.oui.sncf
2nd Class
$35 - $45
1st Class
$55 - $70
Train from Lille Europe to Bruxelles Midi
Ave. Duration
35m
Frequency
Every 4 hours
Estimated price
$25 - $31
Website
en.oui.sncf
2nd Class
$25 - $31
1st Class
$44 - $47
Train from Aeroport Paris-Charles de Gaulle TGV to Bruxelles Midi
Ave. Duration
1h 36m
Frequency
5 times a day
Estimated price
$40 - $60
Website
en.oui.sncf
SNCF

Loosely translated as the French National Railway Corporation, the SNCF is France’s state-owned railway company. It covers the country’s extensive rail network, as well as the TGV and Thalys, France’s two high-speed railway networks. With over 14,000 trains operating daily, it is a fast and efficient way of travelling around the country. The railway network consists of about 32,000km in total, of which 1800km are high-speed lines and 14,500km are electrified.

Rome2rio's guide to SNCF
Contact Details
Phone
+33 9 70 60 99 70
Website
sncf.com
Train from Gare de Lyon-Part-Dieu to Gare de Genève
Ave. Duration
1h 51m
Frequency
Every 2 hours
Estimated price
$28 - $40
Website
en.oui.sncf
2nd Class
$28 - $40
1st Class
$35 - $60
Swiss Railways (SBB/CFF/FFS)

The national railway company of Switzerland, Swiss Railways operates trains throughout the country and adjacent European nations including Germany, France, Italy and Austria. Tickets are sold in two classes - First and Second - with most long-distance trains offering a bistro car serving beverages and snacks. Individual tickets can be bought easily at stands, while a variety of travel passes are on offer to suit different travel needs. Swiss Railways codeshares with American Airlines and Swiss International Air Lines out of Zurich International Airport.

Contact Details
Website
sbb.ch
Train from Lyon-Part-Dieu to Genève
Ave. Duration
1h 58m
Frequency
Twice a week
Estimated price
$50 - $95
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Eurostar
Thalys
Phone
+32 70 66 77 88
Website
thalys.com
Train from Airport Charles de Gaulle to Brussel-Zuid/Midi
Ave. Duration
1h 15m
Frequency
Twice daily
Estimated price
$85 - $120
Website
thalys.com
2nd Class
$85 - $120
1st Class
$110 - $160
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Lyon, Lyon Perrache to Brussels, Brussels-North station
Ave. Duration
11h 10m
Frequency
Twice daily
Estimated price
$45 - $75
Website
flixbus.co.uk
Eurolines FR
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Lyon to Brussels-North
Ave. Duration
13h 18m
Frequency
Twice daily
Estimated price
$85 - $140
Schedules at
eurolines.fr
Other operators
BlaBlaCar

A ridesharing platform with 40 million users, Blablacar gives you access to destinations without worrying about on-the-road chaos. The basic idea is that you carpool with locals who are already planning to drive your route and have space in their car. With some flexibility you’ll get to your destination – often faster and cheaper than other means. On the website or app, enter your departure and arrival points and your date of travel, sift through the profiles of drivers who’ve posted pre-planned drives and find one whose timing and preferences match yours. Request to join the ride, wait be accepted, and pay your share of the set price.

Rome2rio's guide to BlaBlaCar
Contact Details
Website
blablacar.com
Rideshare from Lyon to Brussels
Ave. Duration
8h 31m
Frequency
5 times a day
Estimated price
$54 - $56
Book at
blablacar.co.uk

Want to know more about travelling around Belgium

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Lyon Airport to Brussels Airport is the direct flight which takes 1h 20m.

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Lyon to Brussels bus services, operated by FlixBus, arrive at Brussels, Brussels-North station.

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Lyon to Brussels train services, operated by inOui TGV, arrive at Bruxelles Midi station.

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Yes, the driving distance between Lyon to Brussels is 729 km. It takes approximately 6h 55m to drive from Lyon to Brussels.

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Air France, KLM, Hop! and two other airlines offer flights from Lyon Airport to Brussels Airport.

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Book your Lyon to Brussels train tickets online with Rome2rio.

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Book your Lyon to Brussels bus tickets online with FlixBus and Busbud.

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There are 1016+ hotels available in Brussels. Prices start at $69 USD per night.

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Check out Blablacar's carpooling service for rideshare options between Lyon and Brussels. A great option if you don't have a driver's licence or want to avoid public transport.

Read Rome2rio's guide to Blablacar

The best way to get from Lyon to Lyon Airport is to Rhonexpress which takes 29m and costs 9€ - 15€.

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