There are 9 ways to get from Lyon to Brussels by train, bus, rideshare, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  3 h 50 min

  1. Take the train from Lyon Part Dieu to Bruxelles Midi Tgv

$140 - $160

Cheapest option

Bus Ouibus  •  10 h 27 min

  1. Take the bus from Lyon - Perrache Bus station to Lille Ouibus
  2. Take the bus from Lille to Brussels City Center - Midi Train station Ouibus

$28 - $40

7 alternative options

Bus FlixBus  •  11 h 15 min

  1. Take the bus from Lyon, Lyon Perrache to Brussels, Brussels-North station N769

$45 - $140

Rideshare  •  8 h 31 min

  1. Take the rideshare from Lyon to Brussels 474.9 miles

$54 - $56

Drive  •  6 h 55 min

  1. Drive from Lyon to Brussels 455.5 miles

$95 - $150

Fly Lyon to Brussels  •  4 h 7 min

  1. Fly from Lyon (LYS) to Brussels (BRU) LYS - BRU

$66 - $238

Fly Lyon to Lille Lesquin, train  •  5 h 1 min

  1. Fly from Lyon (LYS) to Lille Lesquin (LIL) LYS - LIL
  2. Take the train from Lille Europe to Bruxelles Midi

$92 - $362

Train to Geneva, fly to Brussels  •  5 h 58 min

  1. Take the train from Lyon Part Dieu to Geneve
  2. Fly from Geneva (GVA) to Brussels (BRU) GVA - BRU

$96 - $257

Fly Lyon to Amsterdam, train  •  6 h 5 min

  1. Fly from Lyon (LYS) to Amsterdam (AMS) LYS - AMS
  2. Take the train from Schiphol (Airport) to Bruxelles-Midi

$86 - $277

Questions & Answers

The cheapest way to get from Lyon to Brussels is to bus which costs 24€ - 35€ and takes 10 h 27 min.

More details

The quickest way to get from Lyon to Brussels is to train which takes 3 h 50 min and costs 120€ - 140€.

More details

The distance between Lyon and Brussels is 569 km. The road distance is 729 km.

Get driving directions

The train from Lyon Part Dieu to Bruxelles Midi takes 3 h 50 min including transfers and departs every four hours.

More details

Yes, there is a direct bus departing from Lyon, Lyon Perrache and arriving at Brussels, Brussels-North station. Services depart twice daily, and operate every day. The journey takes approximately 11 h 15 min.

More details

Yes, there is a direct train departing from Lyon Part Dieu and arriving at Bruxelles Midi. Services depart every four hours, and operate every day. The journey takes approximately 3 h 50 min.

More details

What companies run services between Lyon, France and Brussels, Belgium?

TGV operates a train from Lyon to Brussels every 4 hours. Tickets cost $140 - $160 and the journey takes 3 h 50 min. Alternatively, you can take a bus from Lyon to Brussels via Lille in around 10 h 27 min.

Airlines
Air France
Website
airfrance.com
Flights from Lyon to Brussels
Ave. Duration
1 h 25 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $430
Flights from Lyon to Lille Lesquin
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$100 - $450
Flights from Lyon to Amsterdam
Ave. Duration
1 h 42 min
When
Every day
Estimated price
$100 - $550
Flights from Lyon to Amsterdam via Paris CDG
Ave. Duration
3 h 27 min
When
Every day
Estimated price
$100 - $360
Flights from Lyon to Amsterdam via Brussels
Ave. Duration
3 h 15 min
When
Monday to Friday
Estimated price
$75 - $550
Brussels Airlines
Website
brusselsairlines.com
Flights from Lyon to Brussels
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$60 - $370
Flights from Geneva to Brussels
Ave. Duration
1 h 17 min
When
Every day
Estimated price
$60 - $460
Swiss
Website
swiss.com
Flights from Geneva to Brussels
Ave. Duration
1 h 17 min
When
Every day
Estimated price
$60 - $460
Flights from Geneva to Brussels via Zurich
Ave. Duration
3 h 16 min
When
Every day
Estimated price
$110 - $400
Lufthansa
Website
lufthansa.com
Flights from Lyon to Brussels via Frankfurt
Ave. Duration
3 h 10 min
When
Every day
Estimated price
$160 - $600
Flights from Lyon to Brussels via Munich
Ave. Duration
3 h 30 min
When
Every day
Estimated price
$160 - $600
Flights from Geneva to Brussels via Frankfurt
Ave. Duration
3 h 21 min
When
Every day
Estimated price
$150 - $650
Flights from Lyon to Amsterdam via Munich
Ave. Duration
4 h 20 min
When
Every day
Estimated price
$180 - $550
Flights from Lyon to Amsterdam via Frankfurt
Ave. Duration
4 h 20 min
When
Every day
Estimated price
$180 - $550
Hop!
Website
hop.com
Flights from Lyon to Brussels
Ave. Duration
1 h 25 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $430
Flights from Lyon to Lille Lesquin
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$100 - $450
easyJet
Website
easyjet.com
Flights from Geneva to Brussels
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$45 - $290
Flights from Lyon to Amsterdam
Ave. Duration
1 h 50 min
When
Monday, Thursday and Friday
Estimated price
$60 - $500
Flights from Lyon to Amsterdam via London Luton
Ave. Duration
3 h 55 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$60 - $500
KLM
Website
klm.com
Flights from Geneva to Brussels via Amsterdam
Ave. Duration
3 h 30 min
When
Every day
Estimated price
$150 - $650
Flights from Lyon to Amsterdam
Ave. Duration
1 h 42 min
When
Every day
Estimated price
$100 - $550
British Airways
Website
britishairways.com
Flights from Lyon to Amsterdam via London Heathrow
Ave. Duration
4 h 5 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $650
Train operators
TGV
Phone
0033 892 353535
Website
tgv.com
Train from Lyon Part Dieu to Bruxelles Midi
Ave. Duration
3 h 50 min
Frequency
Every 4 hours
Estimated price
$140 - $160
Website
en.oui.sncf
2nd Class
$140 - $160
1st Class
$190 - $280
Train from Lille Europe to Bruxelles Midi
Ave. Duration
34 min
Frequency
Every 2 hours
Estimated price
$26 - $31
Website
en.oui.sncf
2nd Class
$26 - $31
1st Class
$45 - $48
Train from Lyon Part Dieu to Geneve
Ave. Duration
1 h 44 min
Frequency
Twice daily
Estimated price
$35 - $45
Website
en.oui.sncf
2nd Class
$35 - $45
1st Class
$55 - $70
Eurostar
Website
eurostar.com
Train from Lille Europe Eurostar to Bruxelles-Midi Eurostar
Ave. Duration
35 min
Frequency
Every 3 hours
Estimated price
$30 - $60
Website
eurostar.com
Standard
$30 - $60
Premier
$68 - $69
Thalys
Website
thalys.com
Train from Gare de Lille Europe to Brussels - Midi
Ave. Duration
36 min
Frequency
Once daily
Estimated price
$30 - $55
Website
thalys.com
2nd Class
$30 - $55
1st Class
$55 - $70
Train from Schiphol (Airport) to Bruxelles-Midi
Ave. Duration
1 h 35 min
Frequency
Hourly
Estimated price
$55 - $80
Website
thalys.com
2nd Class
$55 - $80
1st Class
$80 - $110
Dutch Railways (NS)
Phone
+31 30 751 5155
Website
ns.nl
Train from Lille Europe to Brussel-Zuid/Midi
Ave. Duration
36 min
Frequency
Twice daily
Estimated price
$15 - $27
Website
ns.nl
Book at
eurail.com
Train from Schiphol Airport to Brussel-Zuid/Midi
Ave. Duration
1 h 34 min
Frequency
Hourly
Estimated price
$29 - $50
Website
ns.nl
Book at
eurail.com
SNCF
Phone
+33 9 70 60 99 70
Website
sncf.com
Train from Lyon Part Dieu to Geneve
Ave. Duration
1 h 54 min
Frequency
Every 2 hours
Estimated price
$30 - $50
Website
en.oui.sncf
Swiss Railways (SBB/CFF/FFS)
Website
sbb.ch
Train from Lyon-Part-Dieu to Genève
Ave. Duration
1 h 57 min
Frequency
Twice daily
Estimated price
$50 - $100
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Bus operators
Ouibus
Phone
0890715298
Website
ouibus.com
Bus from Lyon - Perrache Bus station to Lille
Ave. Duration
9 h 5 min
Frequency
Every 20 minutes
Estimated price
$24 - $35
Website
Ouibus
Bus from Lille to Brussels City Center - Midi Train station
Ave. Duration
1 h 20 min
Frequency
Every 10 minutes
Estimated price
$4 - $7
Website
Ouibus
FlixBus
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Lyon, Lyon Perrache to Brussels, Brussels-North station
Ave. Duration
11 h 15 min
Frequency
Twice daily
Estimated price
$45 - $80
Website
flixbus.co.uk
Eurolines FR
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Lyon to Brussels-North
Ave. Duration
13 h 18 min
Frequency
Twice daily
Estimated price
$85 - $140
Schedules at
eurolines.fr
Other operators
BlaBlaCar
Website
blablacar.com
Rideshare from Lyon to Brussels
Ave. Duration
8 h 31 min
Frequency
5 times a day
Estimated price
$54 - $56
Book at
blablacar.co.uk

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