Rome2Rio

Lowell to Indianapolis buses

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Trip Overview

The average bus between Lowell and Indianapolis takes 35h 58m and the fastest bus takes 31h 10m. The bus runs, on average, 5 times per week from Lowell to Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

35h 58m
Duration
1,044 mi
Distance
$196
Average price
5 times a week
Frequency

Lowell to Indianapolis bus times

Buses run 5 times a week between Lowell and Indianapolis. The service departs Lowell at 7:50 PM in the evening, which arrives into Indianapolis at 03:00:00. All services require a transfer at Boston and take an average of 35h 58m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

  •  → 

    Arrives +3 days

    Greyhound USAFlixbus USAFlixbus USA2d 7h • 2 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USA31h 10m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USA31h 10m • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USA31h 10m • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USA31h 10m • 2 changes

Frequently asked questions

Want to know about travelling from Lowell to Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Lowell to Indianapolis.ExpandLaunch map view
  • Distance: 1,044.4 mi
  • Duration: 35h 58m

What companies run services between Lowell, MA, USA and Indianapolis, IN, USA?

You can take a bus from Robert B Kennedy Bus Transfer Center to Indianapolis via Boston and New York Midtown in around 23h 12m.

Operators