Rome2Rio

Louisville to Boston buses

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Trip Overview

The average bus between Louisville and Boston takes 36h 32m and the fastest bus takes 32h 20m. There is at least one bus per day from Louisville to Boston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

36h 32m
Duration
1,257 mi
Distance
$247
Average price
Once daily
Frequency

Louisville to Boston bus times

Buses run once daily between Louisville and Boston. The earliest departure is at 2:55 AM at night, and the last departure from Louisville is at 8:00 AM which arrives into Boston at 10:05 PM. All services require a transfer at Lafayette Amtrak Station and take an average of 36h 32m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

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    Arrives next day

    Amtrak ThruwayFlixbus USAFlixbus USA32h 20m • 2 changes
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    Arrives next day

    Amtrak ThruwayFlixbus USAFlixbus USA38h 5m • 2 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Amtrak ThruwayFlixbus USAFlixbus USA34h 30m • 2 changes
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    Arrives next day

    Amtrak ThruwayFlixbus USAFlixbus USA39h 20m • 2 changes

Departing Wednesday, November 18, 2026

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    Arrives next day

    Amtrak ThruwayFlixbus USAFlixbus USA38h 5m • 2 changes

Departing Thursday, November 19, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAFlixbus USA38h 5m • 2 changes

Departing Friday, November 20, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAFlixbus USA32h 20m • 2 changes
  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAFlixbus USA38h 5m • 2 changes

Frequently asked questions

Want to know about travelling from Louisville to Boston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Louisville to Boston.ExpandLaunch map view
  • Distance: 1,257.2 mi
  • Duration: 36h 32m

What companies run services between Louisville, KY, USA and Boston, MA, USA?

You can take a bus from Louisville, KY to Boston via Lafayette Amtrak Station, Lafayette Bus Stop, and New York Midtown in around 27h 24m.

Operators