The average bus between Louisville and Houston takes 26h 40m and the fastest bus takes 23h. There is at least one bus per day from Louisville to Houston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Louisville and Houston. The earliest departure is at 6:00 AM in the morning, and the last departure from Louisville is at 6:20 PM which arrives into Houston at 4:20 PM. All services require a transfer at Nashville Bus Station and take an average of 26h 40m. The schedules shown below are for the next available departures.
Arrives next day


30h 15m • 2 changes
Arrives next day


22h • 2 changes
Arrives next day


30h 15m • 2 changes
Arrives next day


22h • 2 changes
Want to know about travelling from Louisville to Houston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Louisville to Houston. However, there are services departing from Louisville station and arriving at Houston station via Nashville. The journey, including transfers, takes approximately 26h 40m.
Louisville to Houston bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
Louisville to Houston bus services, operated by Amtrak Thruway, arrive at Downtown Houston station.
Book your Louisville to Houston bus tickets online with Amtrak Thruway, Greyhound USA and Flixbus USA.
The distance between Louisville and Houston is 1,292.7 km. The road distance is 1,797 km.
You can take a bus from Louisville, KY to Downtown Houston via Nashville Bus Station and Dallas Bus Station in around 22h 40m.