There are 9 ways to get from Louisville to Boston by plane, bus, bus (Amtrak, Flixbus), train, car, or bus (Amtrak, Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Manchester Airport, bus
best- Fly from Louisville International Airport (SDF) to Manchester Airport (MHT)plane SDF - MHT
- Take the bus from Boston Manchester Airport to Bostonbus
7h 53m$111–567Fly to Theodore Francis Green State Airport, train
cheapest- Fly from Louisville International Airport (SDF) to Theodore Francis Green State Airport (PVD)plane SDF - PVD
- Take the train from TF Green Airport to South Stationtrain
7h 54m$86–419Bus via Brentwood
- Take the bus from Louisville, KY to Nashvillebus
- Take the bus from Nashville, TN to New York, NYbus Ny
- Take the bus from NYC Downtown to Bostonbus
25h 8m$165–218Bus, train via Toledo
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis to Toledobus
- Take the train from Toledo to Bostontrain
25h 16m$474–809Drive 936.8 mi
- Drive from Louisville to Bostoncar 936.8 mi
16h 53m$171–247Fly to Laguardia Airport, train
- Fly from Louisville International Airport (SDF) to Laguardia Airport (LGA)plane SDF - LGA
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
8h 55m$245–909Fly to Newark Liberty International Airport, train
- Fly from Louisville International Airport (SDF) to Newark Liberty International Airport (EWR)plane SDF - EWR
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
8h 54m$214–632Bus
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Newark Penn Stationbus
- Take the bus from Newark Penn Station to Bostonbus
27h 40m$193–314Bus, train (Amtrak)
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the train from Indianapolis to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
29h 56m$643–1,044
Louisville to Boston by bus and train
Comparing Your Travel Options
The cheapest way to get from Louisville to Boston is to bus via Brentwood which costs $160 - $220 and takes 25h 8m.
The fastest way to get from Louisville to Boston is to fly and bus which takes 7h 53m and costs $110 - $600.
No, there is no direct bus from Louisville to Boston. However, there are services departing from Louisville, KY and arriving at Boston via Fulton Station Outbound, Nashville, TN and NYC Downtown. The journey, including transfers, takes approximately 25h 8m.
The distance between Louisville and Boston is 881 miles. The road distance is 942.3 miles.
The best way to get from Louisville to Boston without a car is to bus via Brentwood which takes 25h 8m and costs $160 - $220.
It takes approximately 7h 53m to get from Louisville to Boston, including transfers.
Louisville to Boston bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
Louisville to Boston bus services, operated by Amtrak Thruway, arrive at Nashville station.
Yes, the driving distance between Louisville to Boston is 942 miles. It takes approximately 16h 53m to drive from Louisville to Boston.
Book your Louisville to Boston bus tickets online with Omio.
What companies run services between Louisville, KY, USA and Boston, MA, USA?
You can take a bus from Louisville, KY to Boston via Nashville, Fulton Station Outbound, Nashville, TN, New York, NY, and NYC Downtown in around 25h 8m.
- Website
- southwest.com
Flights from Louisville International Airport to Manchester Airport via Baltimore
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $100–550
Flights from Louisville International Airport to Manchester Airport via Chicago Midway
- Ave. Duration
- 6h 57m
- When
- Monday to Wednesday
- Estimated price
- $120–600
Flights from Louisville International Airport to Theodore Francis Green State Airport via Baltimore
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $75–400
Flights from Louisville International Airport to Theodore Francis Green State Airport via Nashville
- Ave. Duration
- 6h 53m
- When
- Every day
- Estimated price
- $90–440
Flights from Louisville International Airport to Laguardia Airport via Chicago Midway
- Ave. Duration
- 4h 15m
- When
- Tuesday to Friday
- Estimated price
- $160–800
Flights from Louisville International Airport to Laguardia Airport via Nashville
- Ave. Duration
- 4h 45m
- When
- Sunday, Monday, Thursday, Friday, Tuesday, and Wednesday
- Estimated price
- $150–800
- Website
- aa.com
Flights from Louisville International Airport to Manchester Airport via Philadelphia
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $100–550
Flights from Louisville International Airport to Manchester Airport via Reagan Washington
- Ave. Duration
- 6h 8m
- When
- Every day
- Estimated price
- $100–550
Flights from Louisville International Airport to Theodore Francis Green State Airport via Reagan Washington
- Ave. Duration
- 5h 33m
- When
- Every day
- Estimated price
- $75–400
Flights from Louisville International Airport to Theodore Francis Green State Airport via Philadelphia
- Ave. Duration
- 5h 23m
- When
- Tuesday, Wednesday, Monday, Friday, Saturday, and Sunday
- Estimated price
- $75–400
Flights from Louisville International Airport to Laguardia Airport via Reagan Washington
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $120–700
Flights from Louisville International Airport to Newark Liberty International Airport via Charlotte
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $85–440
- Website
- united.com
Flights from Louisville International Airport to Manchester Airport via Washington Dulles
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $100–550
Flights from Louisville International Airport to Theodore Francis Green State Airport via Washington Dulles
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $75–400
Flights from Louisville International Airport to Laguardia Airport via Washington Dulles
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $120–700
Flights from Louisville International Airport to Newark Liberty International Airport
- Ave. Duration
- 2h 17m
- When
- Every day
- Estimated price
- $70–400
Flights from Louisville International Airport to Newark Liberty International Airport via Washington Dulles
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $70–410
- Website
- delta.com
Flights from Louisville International Airport to Theodore Francis Green State Airport via Detroit
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $80–420
Flights from Louisville International Airport to Laguardia Airport
- Ave. Duration
- 2h 13m
- When
- Every day
- Estimated price
- $120–700
Flights from Louisville International Airport to Newark Liberty International Airport via Detroit
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $80–430
- Website
- flybreeze.com
Flights from Louisville International Airport to Theodore Francis Green State Airport via Raleigh/Durham
- Ave. Duration
- 4h 48m
- When
- Wednesday and Saturday
- Estimated price
- $150–900
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Toledo to Boston
- Ave. Duration
- 17h 1m
- Frequency
- Once daily
- Estimated price
- $430–700
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 21m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 21m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Indianapolis to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 22h 8m
- Frequency
- 3 times a week
- Estimated price
- $500–800
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 21m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from TF Green Airport to South Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 47m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 47m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 47m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Boston Manchester Airport to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $9–14
- Website
- Greyhound
Bus from Indianapolis Union Station to Newark Penn Station
- Ave. Duration
- 18h 15m
- Frequency
- Twice daily
- Estimated price
- $130–200
- Website
- Greyhound
Bus from Newark Penn Station to Boston
- Ave. Duration
- 5h 5m
- Frequency
- 4 times a day
- Estimated price
- $45–70
- Website
- Greyhound
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Louisville, KY to Nashville
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Amtrak
- Adult
- $30–50
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
- Phone
- +1 615-939-8887
- tennesseetravel@gotobus.com
- Website
- New York to Tennessee Bus
Bus from Nashville, TN to New York, NY
- Ave. Duration
- 14h 30m
- Frequency
- Once daily
- Estimated price
- $100–120
- Website
- New York to Tennessee Bus
- Adult One-way
- $100–120
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from NYC Downtown to Boston
- Ave. Duration
- 5h
- Frequency
- Every 4 hours
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Bus from Newark Penn Station to Boston
- Ave. Duration
- 4h 30m
- Frequency
- 3 times a day
- Estimated price
- $40–60
- Schedules at
- Flixbus USA
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- Barons Bus
Bus from Indianapolis to Toledo
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- Barons Bus
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 1640+ hotels available in Boston.
















