The average bus between Lille and Milan takes 16h 15m and the fastest bus takes 15h 51m. There is at least one bus per day from Lille to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Lille and Milan. The earliest departure is at 2:00 PM in the afternoon, and the last departure from Lille is at 7:10 PM which arrives into Milan at 11:04 AM. All services require a transfer at Brussels-North train station and take an average of 16h 15m. The schedules shown below are for the next available departures.
Arrives next day


16h 33m • 2 changes
Arrives next day


15h 54m • 2 changes
Arrives next day


16h 28m • 2 changes
Arrives next day


15h 57m • 2 changes
Want to know about travelling from Lille to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lille to Milan. However, there are services departing from Lille station and arriving at Milan station via Brussels-North train station station. The journey, including transfers, takes approximately 16h 15m.
Lille to Milan bus services, operated by FlixBus, depart from Lille station.
Lille to Milan bus services, operated by FlixBus, arrive at Milan station.
The distance between Lille and Milan is 733 km. The road distance is 982 km.
You can take a bus from Lille to Milano, Autostazione Lampugnano via Brussels-North train station, Milan, and via omodeo via cechov in around 15h 36m.