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Lastra a Signa to Rome buses

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Trip Overview

The average bus between Lastra a Signa and Rome takes 4h 54m and the fastest bus takes 3h 34m. The bus service runs several times per day from Lastra a Signa to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 54m
Duration
302 km
Distance
€20
Average price
4 times a day
Frequency

Lastra a Signa to Rome bus times

Buses run 4 times a day between Lastra a Signa and Rome. The earliest departure is at 6:24 AM in the morning, and the last departure from Lastra a Signa is at 8:55 PM which arrives into Rome at 5:25 AM. All services require a transfer at T1 De André and take an average of 4h 54m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Autolinee ToscaneFlixBus3h 35m • 1 change
  •  → 

    Autolinee ToscaneItabus S.p.A.4h 21m • 1 change
  •  → 

    Autolinee ToscaneAutoservizi Salemi Srl4h 48m • 1 change
  •  → 

    Autolinee ToscaneFlixBus3h 36m • 1 change
  • Show more

Departing Thursday, November 12, 2026

  •  → 

    Autolinee ToscaneFlixBus3h 35m • 1 change
  •  → 

    Autolinee ToscaneItabus S.p.A.4h 21m • 1 change
  •  → 

    Autolinee ToscaneFlixBus3h 36m • 1 change
  •  → 

    Arrives next day

    Autolinee ToscaneItabus S.p.A.8h 31m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Autolinee ToscaneFlixBus3h 35m • 1 change
  •  → 

    Autolinee ToscaneItabus S.p.A.4h 21m • 1 change
  •  → 

    Autolinee ToscaneAutoservizi Salemi Srl4h 48m • 1 change
  •  → 

    Autolinee ToscaneFlixBus3h 36m • 1 change
  • Show more

Departing Saturday, November 14, 2026

  •  → 

    Autolinee ToscaneFlixBus3h 35m • 1 change
  •  → 

    Autolinee ToscaneFlixBus3h 53m • 1 change
  •  → 

    Autolinee ToscaneItabus S.p.A.4h 21m • 1 change
  •  → 

    Autolinee ToscaneFlixBus3h 34m • 1 change
  • Show more

Departing Monday, November 16, 2026

  •  → 

    Autolinee ToscaneFlixBus3h 35m • 1 change
  •  → 

    Autolinee ToscaneFlixBus3h 41m • 1 change
  •  → 

    Autolinee ToscaneItabus S.p.A.4h 21m • 1 change
  •  → 

    Autolinee ToscaneAutoservizi Salemi Srl4h 48m • 1 change
  • Show more

Departing Tuesday, November 17, 2026

  •  → 

    Autolinee ToscaneFlixBus3h 35m • 1 change
  •  → 

    Autolinee ToscaneFlixBus3h 41m • 1 change
  •  → 

    Autolinee ToscaneItabus S.p.A.4h 21m • 1 change
  •  → 

    Arrives next day

    Autolinee ToscaneItabus S.p.A.8h 31m • 1 change

Frequently asked questions

Want to know about travelling from Lastra a Signa to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Lastra a Signa to Rome.ExpandLaunch map view
  • Distance: 301.8 km
  • Duration: 4h 54m

What companies run services between Lastra a Signa, Italy and Rome, Italy?

Itabus S.p.A. operates a bus from Florence Villa Constanza Bus Station to Rome Tiburtina Largo Mazzoni every 4 hours. Tickets cost €15–27 and the journey takes 3h 50m. Two other operators also service this route.

Operators