The average bus between Rome and Pisa takes 5h 8m and the fastest bus takes 4h 35m. The bus service runs several times per day from Rome to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Rome and Pisa. The earliest departure is at 12:10 AM at night, and the last departure from Rome is at 6:50 PM which arrives into Pisa at 11:25 PM. All services run direct with no transfers required, and take on average 5h 8m. The schedules shown below are for the next available departures.
Arrives next day
Arrives next day
Want to know about travelling from Rome to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Rome station and arriving at Pisa station. Services depart 5 times a day, and operate Once daily. The journey takes approximately 5h 8m.
Rome to Pisa bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to Pisa bus services, operated by FlixBus, arrive at Pisa station.
Book your Rome to Pisa bus tickets online with FlixBus and AutoLinee Moretti.
The distance between Rome and Pisa is 263.9 km. The road distance is 332 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Pisa 4 times a day. Tickets cost €22–40 and the journey takes 4h 35m. AutoLinee Moretti also services this route 3 times a week.