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Key Largo to Big Pine Key buses

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Trip Overview

The average bus between Key Largo and Big Pine Key takes 2h 13m and the fastest bus takes 2h 10m. The bus service runs several times per day from Key Largo to Big Pine Key. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 13m
Duration
70 mi
Distance
$14
Average price
3 times a day
Frequency

Key Largo to Big Pine Key bus times

Buses run 3 times a day between Key Largo and Big Pine Key. The earliest departure is at 6:30 AM in the morning, and the last departure from Key Largo is at 12:25 PM which arrives into Big Pine Key at 2:40 PM. All services run direct with no transfers required, and take on average 2h 13m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    bus bus 2h 10m • Direct
  •  → 

    bus bus 2h 15m • Direct
  •  → 

    bus bus 2h 15m • Direct

Departing Monday, November 16, 2026

  •  → 

    bus bus 2h 10m • Direct
  •  → 

    bus bus 2h 15m • Direct
  •  → 

    bus bus 2h 15m • Direct

Departing Tuesday, November 17, 2026

  •  → 

    bus bus 2h 10m • Direct
  •  → 

    bus bus 2h 15m • Direct
  •  → 

    bus bus 2h 15m • Direct

Departing Wednesday, November 18, 2026

  •  → 

    bus bus 2h 10m • Direct
  •  → 

    bus bus 2h 15m • Direct

Departing Thursday, November 19, 2026

  •  → 

    bus bus 2h 10m • Direct
  •  → 

    bus bus 2h 15m • Direct

Departing Friday, November 20, 2026

  •  → 

    bus bus 2h 10m • Direct
  •  → 

    bus bus 2h 15m • Direct
  •  → 

    bus bus 2h 15m • Direct

Departing Saturday, November 21, 2026

  •  → 

    bus bus 2h 10m • Direct
  •  → 

    bus bus 2h 15m • Direct
  •  → 

    bus bus 2h 15m • Direct

Frequently asked questions

Want to know about travelling from Key Largo to Big Pine Key? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Key Largo to Big Pine Key.ExpandLaunch map view
  • Distance: 69.5 mi
  • Duration: 2h 13m

What companies run services between Key Largo, FL, USA and Big Pine Key, FL, USA?

Greyhound USA operates a bus from Key Largo Bus Stop to Big Pine Key 3 times a day. Tickets cost $12–19 and the journey takes 2h 15m.

Operators