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Boston to Big Pine Key buses

Find Transport to Big Pine Key

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Trip Overview

The average bus between Boston and Big Pine Key takes 40h 8m and the fastest bus takes 39h 25m. The bus runs, on average, 3 times per week from Boston to Big Pine Key. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

40h 8m
Duration
1,704 mi
Distance
$333
Average price
3 times a week
Frequency

Boston to Big Pine Key bus times

Buses run 3 times a week between Boston and Big Pine Key. The earliest departure is at 3:05 PM in the afternoon, and the last departure from Boston is at 5:15 PM which arrives into Big Pine Key at 8:40 AM. All services require a transfer at Newark Penn Station and take an average of 40h 8m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USA39h 25m • 2 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAGreyhound USA41h 35m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USA39h 25m • 2 changes

Frequently asked questions

Want to know about travelling from Boston to Big Pine Key? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Boston to Big Pine Key.ExpandLaunch map view
  • Distance: 1,704.3 mi
  • Duration: 40h 8m

What companies run services between Boston, MA, USA and Big Pine Key, FL, USA?

You can take a bus from Boston to Big Pine Key via Newark Penn Station and Miami Airport Station in around 36h 25m.

Operators