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Ithaca, NY to Buffalo buses

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Trip Overview

The average bus between Ithaca, NY and Buffalo takes 3h 45m and the fastest bus takes 3h 40m. The bus service runs several times per day from Ithaca, NY to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 45m
Duration
163 mi
Distance
$90
Average price
3 times a day
Frequency

Ithaca, NY to Buffalo bus times

Buses run 3 times a day between Ithaca, NY and Buffalo. The earliest departure is at 5:05 AM in the morning, and the last departure from Ithaca, NY is at 2:15 PM which arrives into Buffalo at 6:00 PM. All services run direct with no transfers required, and take on average 3h 45m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

  •  → 

    bus bus 3h 50m • Direct
  •  → 

    bus bus 3h 45m • Direct

Departing Monday, November 9, 2026

  •  → 

    bus bus 3h 40m • Direct
  •  → 

    bus bus 3h 50m • Direct
  •  → 

    bus bus 3h 45m • Direct

Departing Tuesday, November 10, 2026

  •  → 

    bus bus 3h 40m • Direct
  •  → 

    bus bus 3h 50m • Direct
  •  → 

    bus bus 3h 45m • Direct

Departing Wednesday, November 11, 2026

  •  → 

    bus bus 3h 50m • Direct

Departing Thursday, November 12, 2026

  •  → 

    bus bus 3h 50m • Direct
  •  → 

    bus bus 3h 45m • Direct

Departing Friday, November 13, 2026

  •  → 

    bus bus 3h 40m • Direct
  •  → 

    bus bus 3h 50m • Direct
  •  → 

    bus bus 3h 45m • Direct

Departing Saturday, November 14, 2026

  •  → 

    bus bus 3h 40m • Direct
  •  → 

    bus bus 3h 50m • Direct
  •  → 

    bus bus 3h 45m • Direct

Frequently asked questions

Want to know about travelling from Ithaca, NY to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Ithaca, NY to Buffalo.ExpandLaunch map view
  • Distance: 162.9 mi
  • Duration: 3h 45m

What companies run services between Ithaca, NY, USA and Buffalo, NY, USA?

Flixbus USA operates a bus from Ithaca to Buffalo 3 times a day. Tickets cost $26–40 and the journey takes 3h 45m. Trailways also services this route once daily.

Operators