Rome2Rio

Italy to Santander buses

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Trip Overview

The average bus between Italy and Santander takes 47h 44m and the fastest bus takes 46h 20m. The bus runs, on average, 3 times per week from Italy to Santander. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

47h 44m
Duration
1,991 km
Distance
€200
Average price
3 times a week
Frequency

Italy to Santander bus times

Buses run 3 times a week between Italy and Santander. The earliest departure is at 6:45 AM in the morning, and the last departure from Italy is at 11:00 AM which arrives into Santander at 8:20 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 47h 44m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    Cotral S.p.A.FlixBusFlixBusFlixBus2d 2h • 3 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBusFlixBus46h 20m • 3 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives +2 days

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBusFlixBus46h 20m • 3 changes

Frequently asked questions

Want to know about travelling from Italy to Santander? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Italy to Santander.ExpandLaunch map view
  • Distance: 1,990.7 km
  • Duration: 47h 44m

What companies run services between Italy and Santander, Spain?

You can take a bus from Termini to Estación de autobuses de Santander via Roma, Autostazione Tiburtina, Florence Villa Constanza Bus Station, and Bordeaux in around 28h 59m.

Operators