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  • RailEurope
  • Deutsche Bahn
  • Trenitalia
  • SNCF
  • Flixbus
  • RENFE
  • Ouibus
  • BlaBlaCar
  • Booking.com
  • Skyscanner

There are 10 ways to get from Italy to Santander by plane, night bus, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Milan Linate to Santander  •  7 h 40 min

  1. Fly from Milan Linate (LIN) to Santander (SDR) LIN - SDR

$116 - $514

Cheapest option

Fly Turin to Santander  •  7 h 25 min

  1. Fly from Turin (TRN) to Santander (SDR) TRN - SDR

$68 - $306

8 alternative options

Fly Milan Malpensa to Bilbao, night bus  •  7 h 13 min

  1. Fly from Milan Malpensa (MXP) to Bilbao (BIO) MXP - BIO
  2. Take the night bus from Bilbao to Santander

$87 - $196

Fly Rome to Bilbao, night bus  •  7 h 38 min

  1. Fly from Rome (FCO) to Bilbao (BIO) FCO - BIO
  2. Take the night bus from Bilbao to Santander

$91 - $326

Fly Turin to Bilbao, night bus  •  9 h 51 min

  1. Fly from Turin (TRN) to Bilbao (BIO) TRN - BIO
  2. Take the night bus from Bilbao to Santander

$103 - $224

Train, bus  •  23 h 35 min

  1. Take the train from Roma Termini to Torino Porta Susa Fr
  2. Take the train from Torino Porta Susa to Lyon Part Dieu Tgv
  3. Take the train from Lyon Part Dieu to Massy TGV Tgv
  4. Take the train from Massy TGV to Angers St Laud Tgv
  5. Take the bus from Angers to Santander

$376 - $519

Train  •  25 h 37 min

  1. Take the train from Roma Termini Station to Milano Centrale Station Fr
  2. Take the train from Milano Centrale to Marseille-Saint-Charles Ec
  3. Take the train from Marseille-St-Charles to Madrid-Puerta de Atocha Ave
  4. Take the train from Madrid-Chamartin to Santander A

$305 - $472

Bus Eurolines CH  •  30 h 9 min

  1. Take the bus from Rome to Geneva N1729
  2. Take the bus from Genève to Santander

$142 - $267

Bus Eurolines IT  •  31 h 4 min

  1. Take the bus from Rome Tiburtina to Toulouse Gare Routière
  2. Take the bus from Toulouse to Hub Europe Alsa
  3. Take the bus from Hub Europe Alsa to Santander

$107 - $152

Drive  •  17 h 12 min

  1. Drive from Rome to Santander 1128.5 miles

$270 - $400

Questions & Answers

The cheapest way to get from Italy to Santander is to fly and night bus which costs 75€ - 170€ and takes 7 h 13 min.

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The quickest way to get from Italy to Santander is to fly and night bus which costs 75€ - 170€ and takes 7 h 13 min.

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No, there is no direct bus from Italy to Santander. However, there are services departing from Via S. Croce In Gerusalemme/Statilia and arriving at Santander via Rome and Genève. The journey, including transfers, takes approximately 30 h 9 min.

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No, there is no direct train from Italy station to Santander. However, there are services departing from Roma Termini Station and arriving at Santander via Milano Centrale, Marseille-St-Charles, Madrid Atocha and Madrid-Chamartin. The journey, including transfers, takes approximately 25 h 37 min.

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The distance between Italy and Santander is 1340 km. The road distance is 1805.6 km.

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The best way to get from Italy to Santander without a car is to train and bus which takes 23 h 35 min and costs 320€ - 460€.

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It takes approximately 7 h 40 min to get from Italy to Santander, including transfers.

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Italy to Santander bus services, operated by FlixBus, depart from Rome station.

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Italy to Santander train services, operated by ItaloTreno, arrive at Roma Termini Station.

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The best way to get from Italy to Santander is to fly which takes 7 h 40 min and costs 100€ - 450€. Alternatively, you can train, which costs 260€ - 410€ and takes 25 h 37 min, you could also bus, which costs 120€ - 240€ and takes 30 h 9 min.

Mode details

Map of how to get from Italy to Santander.
Launch map view
  • Distance: 837.5 miles
  • Duration: 7 h 40 min

What companies run services between Italy and Santander, Spain?

Iberia and Alitalia fly from Milan to Santander every 3 hours. Alternatively, you can take a train from Rome to Santander via Milano Centrale Station, Milano Centrale, Marseille-Saint-Charles, Marseille-St-Charles, Madrid-Puerta de Atocha, Madrid Atocha, Madrid Chamartín, and Madrid-Chamartin in around 25 h 37 min.

Airlines
Iberia
Website
iberia.com
Flights from Milan Linate to Santander via Madrid
Ave. Duration
5 h 28 min
When
Every day
Estimated price
$100 - $550
Flights from Milan Malpensa to Bilbao
Ave. Duration
1 h 55 min
When
Thursday and Sunday
Estimated price
$70 - $300
Flights from Milan Malpensa to Bilbao via Barcelona
Ave. Duration
4 h 23 min
When
Every day
Estimated price
$70 - $300
Flights from Milan Malpensa to Bilbao via Madrid
Ave. Duration
4 h 40 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $290
Flights from Turin to Santander via Madrid
Ave. Duration
6 h 20 min
When
Every day
Estimated price
$110 - $550
Flights from Turin to Santander via Barcelona, Madrid
Ave. Duration
6 h 25 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$100 - $490
Flights from Turin to Santander via Barcelona
Ave. Duration
3 h 50 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$50 - $280
Flights from Rome to Bilbao
Ave. Duration
2 h 25 min
When
Wednesday and Saturday
Estimated price
$90 - $600
Flights from Rome to Bilbao via Barcelona
Ave. Duration
4 h 18 min
When
Every day
Estimated price
$90 - $600
Flights from Rome to Bilbao via Madrid
Ave. Duration
4 h 50 min
When
Every day
Estimated price
$90 - $500
Flights from Rome to Bilbao via Paris CDG
Ave. Duration
4 h 57 min
When
Monday, Friday and Sunday
Estimated price
$90 - $600
Flights from Turin to Bilbao via Madrid
Ave. Duration
5 h 1 min
When
Every day
Estimated price
$170 - $430
Flights from Turin to Bilbao via Barcelona
Ave. Duration
4 h 35 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$140 - $400
Lufthansa
Website
lufthansa.com
Flights from Milan Malpensa to Bilbao via Frankfurt
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$180 - $470
Flights from Milan Malpensa to Bilbao via Munich
Ave. Duration
4 h 33 min
When
Every day
Estimated price
$180 - $470
Flights from Milan Malpensa to Bilbao via Dusseldorf
Ave. Duration
4 h 30 min
When
Every day
Estimated price
$110 - $390
Flights from Rome to Bilbao via Munich
Ave. Duration
4 h 52 min
When
Every day
Estimated price
$220 - $700
Flights from Rome to Bilbao via Frankfurt
Ave. Duration
5 h 25 min
When
Every day
Estimated price
$220 - $700
Flights from Turin to Bilbao via Munich
Ave. Duration
4 h 35 min
When
Every day
Estimated price
$190 - $750
Flights from Turin to Bilbao via Frankfurt
Ave. Duration
7 h 38 min
When
Every day
Estimated price
$190 - $750
Vueling Airlines
Website
vueling.com
Flights from Milan Malpensa to Bilbao
Ave. Duration
1 h 55 min
When
Thursday and Sunday
Estimated price
$70 - $300
Flights from Milan Malpensa to Bilbao via Barcelona
Ave. Duration
4 h 23 min
When
Every day
Estimated price
$70 - $300
Flights from Turin to Santander via Barcelona
Ave. Duration
3 h 50 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$50 - $280
Flights from Rome to Bilbao
Ave. Duration
2 h 25 min
When
Wednesday and Saturday
Estimated price
$90 - $600
Flights from Rome to Bilbao via Barcelona
Ave. Duration
4 h 18 min
When
Every day
Estimated price
$90 - $600
Flights from Rome to Bilbao via Paris CDG
Ave. Duration
4 h 57 min
When
Monday, Friday and Sunday
Estimated price
$90 - $600
Flights from Turin to Bilbao via Barcelona
Ave. Duration
4 h 35 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$140 - $400
Flights from Turin to Bilbao via London Gatwick
Ave. Duration
5 h 25 min
When
Thursday
Estimated price
$140 - $400
easyJet
Website
easyjet.com
Flights from Milan Malpensa to Bilbao
Ave. Duration
1 h 55 min
When
Monday
Estimated price
$55 - $190
Flights from Rome to Bilbao via Geneva
Ave. Duration
4 h 10 min
When
Saturday
Estimated price
$60 - $310
Flights from Turin to Bilbao via Bristol
Ave. Duration
5 h 40 min
When
Sunday
Estimated price
$75 - $400
Flights from Turin to Bilbao via Manchester
Ave. Duration
6 h
When
Sunday
Estimated price
$85 - $450
British Airways
Website
britishairways.com
Flights from Milan Linate to Santander via Madrid
Ave. Duration
6 h 12 min
When
Monday to Saturday
Estimated price
$110 - $650
Flights from Turin to Bilbao via London Gatwick
Ave. Duration
5 h 25 min
When
Thursday
Estimated price
$140 - $400
Air Europa
Website
aireuropa.com
Flights from Milan Malpensa to Bilbao via Madrid
Ave. Duration
4 h 35 min
When
Monday, Tuesday, Wednesday, Thursday and Sunday
Estimated price
$95 - $360
Flights from Rome to Bilbao via Madrid
Ave. Duration
5 h 32 min
When
Every day
Estimated price
$140 - $650
Air France
Website
airfrance.com
Flights from Rome to Bilbao via Paris CDG
Ave. Duration
4 h 55 min
When
Every day
Estimated price
$150 - $1,100
Flights from Turin to Bilbao via Paris CDG
Ave. Duration
7 h 5 min
When
Every day
Estimated price
$180 - $500
KLM
Website
klm.com
Flights from Turin to Bilbao via Amsterdam
Ave. Duration
5 h
When
Monday to Saturday
Estimated price
$200 - $430
Flights from Turin to Bilbao via Paris CDG
Ave. Duration
7 h 5 min
When
Every day
Estimated price
$180 - $500
Brussels Airlines
Website
brusselsairlines.com
Flights from Rome to Bilbao via Brussels
Ave. Duration
5 h
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$95 - $700
Flights from Turin to Bilbao via Brussels
Ave. Duration
8 h 35 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $750
Alitalia
Website
alitalia.com
Flights from Rome to Bilbao via Madrid
Ave. Duration
5 h 32 min
When
Every day
Estimated price
$140 - $650
Swiss
Website
swiss.com
Flights from Milan Malpensa to Bilbao via Zurich
Ave. Duration
4 h 15 min
When
Thursday, Friday, Saturday and Sunday
Estimated price
$220 - $950
Eurowings
Website
eurowings.com
Flights from Milan Malpensa to Bilbao via Dusseldorf
Ave. Duration
4 h 30 min
When
Every day
Estimated price
$110 - $390
Volotea
Website
volotea.com
Flights from Turin to Santander via Sevilla
Ave. Duration
6 h
When
Thursday
Estimated price
$100 - $470
Train operators
Trenitalia Frecce

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Roma Termini to Torino Porta Susa
Ave. Duration
4 h 25 min
Frequency
Hourly
Estimated price
$80 - $120
Website
orario.trenitalia.com
Train from Roma Termini to Milano Centrale
Ave. Duration
3 h 20 min
Frequency
Hourly
Estimated price
$65 - $95
Website
orario.trenitalia.com
inOui TGV
Phone
0033 892 353535
Website
en.oui.sncf
Train from Torino Porta Susa to Lyon Part Dieu
Ave. Duration
4 h 17 min
Frequency
4 times a week
Estimated price
$60 - $70
Website
en.oui.sncf
2nd Class
$60 - $70
1st Class
$85 - $120
Train from Lyon Part Dieu to Massy TGV
Ave. Duration
2 h 4 min
Frequency
Every 4 hours
Estimated price
$85 - $95
Website
en.oui.sncf
2nd Class
$85 - $95
1st Class
$110 - $170
Train from Massy TGV to Angers St Laud
Ave. Duration
1 h 33 min
Frequency
Every 2 hours
Estimated price
$55 - $70
Website
en.oui.sncf
2nd Class
$55 - $70
1st Class
$85 - $110
ItaloTreno
Phone
+39 060708
Website
italotreno.it
Train from Roma Termini Station to Milano Centrale Station
Ave. Duration
2 h 59 min
Frequency
Hourly
Estimated price
$40 - $65
Website
italotreno.it
Trenitalia Eurocity

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Milano Centrale to Marseille-Saint-Charles
Ave. Duration
7 h 26 min
Frequency
Once daily
Estimated price
$80 - $110
Website
orario.trenitalia.com
SNCF

Loosely translated as the French National Railway Corporation, the SNCF is France’s state-owned railway company. It covers the country’s extensive rail network, as well as the TGV and Thalys, France’s two high-speed railway networks. With over 14,000 trains operating daily, it is a fast and efficient way of travelling around the country. The railway network consists of about 32,000km in total, of which 1800km are high-speed lines and 14,500km are electrified.

Rome2rio's guide to SNCF
Contact Details
Phone
+33 9 70 60 99 70
Website
sncf.com
Train from Marseille-St-Charles to Madrid-Puerta de Atocha
Ave. Duration
7 h 44 min
Frequency
6 times a week
Estimated price
$130 - $200
Website
en.oui.sncf
Spanish Railways (RENFE)

Based in Madrid, Renfe is a state-owned train operator, that connects cities across Spain and neighbouring countries including Portugal, France, Germany, Switzerland, and the Netherlands. Renfe’s extensive network means most destinations offer multiple trains a day, with the most popular routes normally offering a train each hour. Locally known as AVE, the high-speed trains can reach speeds of up to 350km/h, making travel between major cities very efficient. Comfort is key in a Renfe train, with seats with footrests in all three classes of travel: Standard, Club and First. Each seat has an individual light, a pull-down table and an electrical outlet for in Club and First classes. There is free WiFi for first class passengers and for those with a + Renfe card.

Rome2rio's guide to Spanish Railways (RENFE)
Contact Details
Phone
902 320 320
Website
renfe.com
Train from Madrid-Chamartin to Santander
Ave. Duration
4 h 11 min
Frequency
Every 4 hours
Estimated price
$50 - $65
Website
renfe.com
Bus operators
ALSA

A Spanish subsidiary of National Express, ALSA provides bus and coach services across Spain and neighbouring countries including Portugal, France, Germany, the Netherlands, Italy, Poland and Malta. Founded in 1923, ALSA values service and the customer experience. Buses are equipped with communal TV screens showing movies, individual behind-seat screens, ALSA radio, app for books and music, and free WiFi so you’re never bored on your journey. ALSA services are accessible to people with disabilities, and guide dogs are welcome on all journeys. Flexibility is another highlight of an ALSA journey, with three types of tickets on offer - Frequent Traveller Pass, Share Pass and ALSA Pass, along with discounts for senior citizens, students and children.

Contact Details
Phone
+34 902 42 22 42
Website
alsa.es
Night bus from Bilbao to Santander
Ave. Duration
1 h 30 min
Frequency
Hourly
Estimated price
$18 - $28
Website
alsa.com
Eurolines FR
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Angers to Santander
Ave. Duration
7 h 14 min
Frequency
3 times a week
Estimated price
$95 - $170
Schedules at
eurolines.fr
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Rome to Geneva
Ave. Duration
10 h
Frequency
Once daily
Estimated price
$55 - $95
Website
flixbus.co.uk
Eurolines CH
Phone
0041 (0) 844 257 224
Website
eurolines.ch
Bus from Genève to Santander
Ave. Duration
17 h 45 min
Frequency
3 times a week
Estimated price
$85 - $170
Book at
eurolines.ch
Ouibus

As the bus subsidiary of French railway SNCF, Ouibus offers comfortable, eco-friendly coaches serving 35 French cities and 11 European cities at affordable fares. Ouibus journeys are safe and comfortable, with the four-star coaches offering power outlets, restrooms and WiFi. All Ouibus stations are located close to town centres for easy access to public transport. Getting on one of the 130 daily journeys is easy - electronic travel documents include your ticket and a personalised mini-guide with handy information.

Contact Details
Phone
0890715298
Website
ouibus.com
Bus from Toulouse to Hub Europe Alsa
Ave. Duration
5 h
Frequency
3 times a week
Estimated price
$13 - $19
Website
Ouibus
Bus from Hub Europe Alsa to Santander
Ave. Duration
2 h 40 min
Frequency
3 times a week
Estimated price
$7 - $11
Website
Ouibus

Want to know more about travelling around Spain

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

There is no direct flight from Milan Linate Airport to Santander Airport. The quickest flight takes 4 h 45 min and has one stopover.

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Italy to Santander bus services, operated by Eurolines CH, arrive at Santander station.

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Italy to Santander train services, operated by Spanish Railways (RENFE), arrive at Santander station.

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Yes, the driving distance between Italy to Santander is 1806 km. It takes approximately 17 h 12 min to drive from Italy to Santander.

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Alitalia and Iberia offer flights from Milan Linate Airport to Santander Airport.

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There are 528+ hotels available in Santander. Prices start at $52 USD per night.

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The best way to get from Italy to Milan Linate Airport is to line 73 bus which takes 31 min and costs 1€ - 2€.

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