Rome2Rio

Irvine to Durham buses

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Trip Overview

The average bus between Irvine and Durham takes 2d 18h and the fastest bus takes 2d 17h. There is at least one bus per day from Irvine to Durham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 18h
Duration
2,698 mi
Distance
$586
Average price
Once daily
Frequency

Irvine to Durham bus times

Buses run once daily between Irvine and Durham. The earliest departure is at 5:45 AM in the morning, and the last departure from Irvine is at 10:46 PM which arrives into Durham at 2:10 AM. All services require a transfer at Artic - Dock 4 and take an average of 2d 18h. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives +3 days

    OCTAGreyhound USAGreyhound USAGreyhound USAFlixbus USA2d 17h • 4 changes
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    Arrives +4 days

    OCTAFlixbus USAGreyhound USAGreyhound USAFlixbus USA3d • 4 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +3 days

    OCTAGreyhound USAGreyhound USAGreyhound USAFlixbus USA2d 17h • 4 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +3 days

    OCTAFlixbus USAGreyhound USAGreyhound USAFlixbus USA2d 17h • 4 changes
  •  → 

    Arrives +3 days

    OCTAGreyhound USAGreyhound USAGreyhound USAFlixbus USA2d 17h • 4 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +3 days

    OCTAFlixbus USAGreyhound USAGreyhound USAFlixbus USA2d 17h • 4 changes
  •  → 

    Arrives +3 days

    OCTAGreyhound USAGreyhound USAGreyhound USAFlixbus USA2d 17h • 4 changes

Frequently asked questions

Want to know about travelling from Irvine to Durham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Irvine to Durham.ExpandLaunch map view
  • Distance: 2,697.9 mi
  • Duration: 2d 18h

What companies run services between Irvine, CA, USA and Durham, NC, USA?

You can take a bus from Main-Harvard to Durham via Artic - Dock 4, Anaheim Regional Transportation Intermodal Center, Los Angeles Union Station, Dallas Bus Station, and Atlanta Bus Station in around 2d 12h.

Operators