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How to get fromIrvine to Durhamby plane, bus (Greyhound, Flixbus), train (Amtrak), car or train

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There are 6 ways to get from Irvine to Durham by plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Raleigh-Durham International Airport

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Raleigh-Durham International Airport (RDU)planeSNA - RDU
    6h 42m
    $178–754
  2. Bus

    1. Take the bus from Anaheim to Los Angeles Union Stationbus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus
    4. Take the bus from Atlanta Bus Station to Durhambus
    2d 12h
    $245–612
  3. Train (Amtrak)

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain
    2. Take the train from Chicago Union Station to Carytrain
    2d 22h
    $362–3,516
  4. Drive 2,482.8 mi

    1. Drive from Irvine to Durhamcar2,482.8 mi
    40h 29m
    $454–655
  5. Train to Los Angeles International Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Tustin to L.A. Union Stationtrain
    2. Fly from Los Angeles International Airport (LAX) to Raleigh-Durham International Airport (RDU)planeLAX - RDU
    8h 53m
    $189–578
  6. Fly John Wayne Airport Orange County to Charlotte Douglas International Airport, train

    1. Fly from John Wayne Airport Orange County (SNA) to Charlotte Douglas International Airport (CLT)planeSNA - CLT
    2. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain
    9h 30m
    $311–741

Irvine to Durham by bus

Calendar14Weekly Buses
Duration2d 12hAverage Duration
Ticket$245Cheapest Price
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Questions & Answers

What companies run services between Irvine, CA, USA and Durham, NC, USA?

Breeze Airways, Delta, and two other airlines fly from John Wayne Airport Orange County (SNA) to Raleigh-Durham International Airport (RDU) 4 times a day. Alternatively, you can take a bus from Main-Harvard to Durham via Artic - Dock 4, Anaheim, Los Angeles Union Station, Dallas Bus Station, and Atlanta Bus Station in around 2d 12h.

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