The average bus between Indianapolis and Houston takes 25h 32m and the fastest bus takes 25h 15m. There is at least one bus per day from Indianapolis to Houston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Indianapolis and Houston. The earliest departure is at 11:15 AM in the morning, and the last departure from Indianapolis is at 4:05 PM which arrives into Houston at 4:20 PM. All services require a transfer at Nashville Bus Station and take an average of 25h 32m. The schedules shown below are for the next available departures.
Arrives next day


24h 50m • 2 changes
Arrives next day


24h 15m • 2 changes
Arrives next day


24h 50m • 2 changes
Arrives next day


24h 15m • 2 changes
Want to know about travelling from Indianapolis to Houston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Indianapolis to Houston. However, there are services departing from Indianapolis station and arriving at Houston station via Nashville Bus Station station. The journey, including transfers, takes approximately 25h 32m.
Indianapolis to Houston bus services, operated by Amtrak Thruway, depart from Indianapolis Union Station.
Indianapolis to Houston bus services, operated by Amtrak Thruway, arrive at Downtown Houston station.
Book your Indianapolis to Houston bus tickets online with Amtrak Thruway, Greyhound USA and Flixbus USA.
The distance between Indianapolis and Houston is 1,392.8 km. The road distance is 1,982 km.
You can take a bus from Indianapolis Union Station to Downtown Houston via Nashville Bus Station and Dallas Bus Station in around 25h.