The average bus between Indiana and Missouri takes 12h 13m and the fastest bus takes 10h 35m. The bus service runs several times per day from Indiana to Missouri. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Indiana and Missouri. The earliest departure is at 5:00 AM in the morning, and the last departure from Indiana is at 8:05 PM which arrives into Missouri at 6:00 AM. All services require a transfer, and take on average 12h 13m. The schedules shown below are for the next available departures.

14h 10m • 1 change

9h 35m • 1 change
Arrives next day

9h 55m • 1 change

14h 10m • 1 change

9h 35m • 1 change
Arrives next day

9h 55m • 1 change

14h 10m • 1 change

9h 35m • 1 change
Arrives next day

9h 55m • 1 change

14h 10m • 1 change

9h 35m • 1 change
Arrives next day

9h 55m • 1 change

14h 10m • 1 change

9h 35m • 1 change
Arrives next day

9h 55m • 1 change
Want to know about travelling from Indiana to Missouri? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Indiana to Missouri. However, there are services departing from Indiana station and arriving at Missouri station via St Louis Bus Station station. The journey, including transfers, takes approximately 12h 13m.
Indiana to Missouri bus services, operated by Greyhound USA, depart from Indianapolis Union Station.
Indiana to Missouri bus services, operated by Greyhound USA, arrive at Kansas City Bus Station.
Book your Indiana to Missouri bus tickets online with Greyhound USA.
The distance between Indiana and Missouri is 574.5 km. The road distance is 788 km.
You can take a bus from Indianapolis Union Station to Kansas City Bus Station via St Louis Bus Station in around 9h 25m.