The average bus between Hyannis and Hartford takes 4h 23m and the fastest bus takes 3h 40m. The bus service runs several times per day from Hyannis to Hartford. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Hyannis and Hartford. The earliest departure is at 4:30 AM at night, and the last departure from Hyannis is at 7:00 PM which arrives into Hartford at 11:20 PM. All services require a transfer, and take on average 4h 23m. The schedules shown below are for the next available departures.

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4h 5m • 1 changeWant to know about travelling from Hyannis to Hartford? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hyannis to Hartford. However, there are services departing from Hyannis station and arriving at Hartford Union Station via Boston station. The journey, including transfers, takes approximately 4h 23m.
Hyannis to Hartford bus services, operated by Peter Pan Bus Lines, depart from Hyannis station.
Hyannis to Hartford bus services, operated by Greyhound USA, arrive at Hartford Union Station.
Book your Hyannis to Hartford bus tickets online with Omio.
The distance between Hyannis and Hartford is 199.8 km. The road distance is 227 km.
You can take a bus from Hyannis to Hartford Union Station via Boston in around 3h 46m.