The average bus between Houston and Key West takes 42h 43m and the fastest bus takes 42h 9m. The bus runs, on average, 5 times per week from Houston to Key West. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between Houston and Key West. The earliest departure is at 5:50 PM in the evening, and the last departure from Houston is at 5:52 PM which arrives into Key West at 1:02 PM. All services require a transfer at Magnolia Transit Center and take an average of 42h 43m. The schedules shown below are for the next available departures.
Want to know about travelling from Houston to Key West? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Houston to Key West. However, there are services departing from Houston station and arriving at Key West station via Tallahassee. The journey, including transfers, takes approximately 42h 43m.
Houston to Key West bus services, operated by Metropolitan Transit Harris County, depart from Houston Bus Station.
Houston to Key West bus services, operated by Metropolitan Transit Harris County, arrive at N Roosevelt & 3rd Street station.
Book your Houston to Key West bus tickets online with Metropolitan Transit Harris County, Greyhound USA and 2 other operators.
The distance between Houston and Key West is 1,461.8 km. The road distance is 2,235 km.
You can take a bus from Louisiana St @ Preston St to N Roosevelt & 3rd Street via Magnolia Transit Center, Houston Bus Station, Tallahassee, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 34h 39m.