Hotel Domidea, Rome to Sistine Chapel Buses

Trip Overview

The average bus between Hotel Domidea, Rome and Sistine Chapel takes 1h 13m and the fastest bus takes 1h 2m. The bus service runs several times per day from Hotel Domidea, Rome to Sistine Chapel. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

1h 13m
Duration: 23 km
Distance: €16
Average price: Every 4 hours
Frequency

Bus, line 64 bus

best

Take the bus from Costi to Plebiscitobus n543
Take the bus from Plebiscito to Cavalleggeri/S. Pietrobus 62 / ...

1h 26m

€2–18

Hotel Domidea, Rome to Sistine Chapel bus times

Buses run every 4 hours between Hotel Domidea, Rome and Sistine Chapel. The earliest departure is at 12:54 AM at night, and the last departure from Hotel Domidea, Rome is at 4:48 AM which arrives into Sistine Chapel at 5:52 AM. All services require a transfer at Costi and take an average of 1h 13m. The schedules shown below are for the next available departures.

Departing Friday, October 9, 2026

2:49 AM → 4:01 AM
1h 12m • 1 change
3:28 AM → 4:46 AM
1h 18m • 1 change
4:08 AM → 5:21 AM
1h 13m • 1 change
4:48 AM → 5:52 AM
1h 4m • 1 change

Departing Saturday, October 10, 2026

12:54 AM → 2:10 AM
1h 16m • 1 change
1:29 AM → 2:47 AM
1h 18m • 1 change
2:09 AM → 3:16 AM
1h 7m • 1 change
2:49 AM → 4:01 AM
1h 12m • 1 change
Show more

Departing Sunday, October 11, 2026

12:54 AM → 2:10 AM
1h 16m • 1 change
1:29 AM → 2:47 AM
1h 18m • 1 change
2:09 AM → 3:16 AM
1h 7m • 1 change
2:49 AM → 4:01 AM
1h 12m • 1 change
Show more

Departing Monday, October 12, 2026

12:54 AM → 2:07 AM
1h 13m • 1 change
1:29 AM → 2:50 AM
1h 21m • 1 change
2:09 AM → 3:16 AM
1h 7m • 1 change
2:49 AM → 4:01 AM
1h 12m • 1 change
Show more

Departing Tuesday, October 13, 2026

12:54 AM → 2:10 AM
1h 16m • 1 change
1:29 AM → 2:50 AM
1h 21m • 1 change
2:09 AM → 3:16 AM
1h 7m • 1 change
2:49 AM → 4:01 AM
1h 12m • 1 change
Show more

Departing Wednesday, October 14, 2026

12:54 AM → 2:10 AM
1h 16m • 1 change
1:29 AM → 2:50 AM
1h 21m • 1 change
2:09 AM → 3:16 AM
1h 7m • 1 change
2:49 AM → 4:01 AM
1h 12m • 1 change
Show more

Departing Thursday, October 15, 2026

12:54 AM → 2:10 AM
1h 16m • 1 change
1:29 AM → 2:50 AM
1h 21m • 1 change
2:09 AM → 3:16 AM
1h 7m • 1 change
2:49 AM → 4:01 AM
1h 12m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Hotel Domidea, Rome to Sistine Chapel? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

What companies run services between Hotel Domidea, Rome, Italy and Sistine Chapel, Vatican City?

You can take a vehicle from Hotel Domidea, Rome to Sistine Chapel via Costi, Plebiscito, and Cavalleggeri/S. Pietro in around 1h 26m.

Operators

Hotel Domidea, Rome to Sistine Chapel buses

Find Transport to Sistine Chapel

Trip Overview

Bus, line 64 bus

Hotel Domidea, Rome to Sistine Chapel bus times

Departing Friday, October 9, 2026

2:49 AM → 4:01 AM

3:28 AM → 4:46 AM

4:08 AM → 5:21 AM

4:48 AM → 5:52 AM

Departing Saturday, October 10, 2026

12:54 AM → 2:10 AM

1:29 AM → 2:47 AM

2:09 AM → 3:16 AM

2:49 AM → 4:01 AM

Departing Sunday, October 11, 2026

12:54 AM → 2:10 AM

1:29 AM → 2:47 AM

2:09 AM → 3:16 AM

2:49 AM → 4:01 AM

Departing Monday, October 12, 2026

12:54 AM → 2:07 AM

1:29 AM → 2:50 AM

2:09 AM → 3:16 AM

2:49 AM → 4:01 AM

Departing Tuesday, October 13, 2026

12:54 AM → 2:10 AM

1:29 AM → 2:50 AM

2:09 AM → 3:16 AM

2:49 AM → 4:01 AM

Departing Wednesday, October 14, 2026

12:54 AM → 2:10 AM

1:29 AM → 2:50 AM

2:09 AM → 3:16 AM

2:49 AM → 4:01 AM

Departing Thursday, October 15, 2026

12:54 AM → 2:10 AM

1:29 AM → 2:50 AM

2:09 AM → 3:16 AM

2:49 AM → 4:01 AM

Frequently asked questions

What companies run services between Hotel Domidea, Rome, Italy and Sistine Chapel, Vatican City?

Bus from Costi to Plebiscito

Bus from Plebiscito to Cavalleggeri/S. Pietro

Bus from Malatesta to Crescenzio/Risorgimento

Bus trips from Hotel Domidea, Rome

Bus trips to Sistine Chapel

Alternative transport options