The average bus between Heidelberg and Lyon takes 10h 37m and the fastest bus takes 9h 44m. The bus service runs several times per day from Heidelberg to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Heidelberg and Lyon. The earliest departure is at 12:26 AM at night, and the last departure from Heidelberg is at 8:11 PM which arrives into Lyon at 8:15 AM. All services require a transfer, and take on average 10h 37m. The schedules shown below are for the next available departures.

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11h 44m • 1 change
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12h 39m • 1 change

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12h 14m • 1 change

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11h 44m • 1 change
Want to know about travelling from Heidelberg to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Heidelberg to Lyon. However, there are services departing from Heidelberg station and arriving at Lyon station via Karlsruhe central train station station. The journey, including transfers, takes approximately 10h 37m.
Heidelberg to Lyon bus services, operated by FlixBus, depart from Heidelberg Post Waypoint station.
Heidelberg to Lyon bus services, operated by FlixBus, arrive at Lyon station.
Book your Heidelberg to Lyon bus tickets online with FlixBus and BlaBlaCar Bus.
The distance between Heidelberg and Lyon is 498.6 km. The road distance is 646 km.
You can take a bus from Heidelberg Post Waypoint to Lyon via Karlsruhe central train station in around 9h 44m.