The average bus between Harlem and Chicago takes 20h 2m and the fastest bus takes 17h 58m. The bus service runs several times per day from Harlem to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Harlem and Chicago. The earliest departure is at 9:38 AM in the morning, and the last departure from Harlem is at 8:27 PM which arrives into Chicago at 1:25 PM. All services require a transfer at 42 St-Port Authority Bus Terminal and take an average of 20h 2m. The schedules shown below are for the next available departures.
Arrives next day

20h 22m • 1 change
Arrives next day

17h 13m • 1 change
Arrives next day

20h 27m • 1 change
Arrives next day

17h 4m • 1 change
Arrives next day

20h 32m • 1 change
Arrives next day

16h 58m • 1 change
Arrives next day

20h 32m • 1 change
Arrives next day

16h 58m • 1 change
Want to know about travelling from Harlem to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Harlem to Chicago. However, there are services departing from Harlem station and arriving at Chicago station via Baltimore Downtown Bus Station station. The journey, including transfers, takes approximately 20h 2m.
Harlem to Chicago bus services, operated by MTA Bus Company, depart from Port Authority Bus Terminal station.
Harlem to Chicago bus services, operated by MTA Bus Company, arrive at Chicago Bus Station.
The distance between Harlem and Chicago is 1,147.1 km. The road distance is 1,591 km.
You can take a subway from 125 St to Chicago Bus Station via 42 St-Port Authority Bus Terminal, Port Authority Bus Terminal, and Baltimore Downtown Bus Station in around 23h 47m.