There are 10 ways to get from Guelph to Chicago by train, plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train to Toronto, fly to Chicago O'Hare  •  6 h 3 min

  1. YYZ - ORD

$130 - $430

Cheapest option

Bus  •  11 h 24 min

  1. 5503 / 5502 / ...
  2. 5515 / ...

$49 - $129

8 alternative options

Train to Toronto Island, fly to Chicago Midway  •  5 h 48 min

  1. YTZ - MDW

$129 - $432

Train, bus to Buffalo, fly to Chicago Midway  •  8 h 2 min

  1. BUF - MDW

$178 - $510

Train, bus to Buffalo, fly to Chicago O'Hare  •  8 h 26 min

  1. BUF - ORD

$168 - $481

Train to Toronto, fly to Milwaukee, train  •  8 h 20 min

  1. YYZ - MKE

$195 - $556

Train  •  11 h 7 min

  1. VIA Rail
  2. Blue Water

$88 - $247

Train Amtrak, bus  •  13 h 59 min

$91 - $253

Train, bus Megabus  •  21 h 19 min

$65 - $160

Drive  •  8 h 2 min

  1. 476.5 miles

$60 - $95

What companies run services between Guelph, ON, Canada and Chicago, IL, USA?

You can take a train from Guelph to Chicago via Sarnia and Port Huron Amtrak in around 11 h 7 min. Alternatively, you can take a bus from Guelph to Chicago via London, ON in around 11 h 24 min.

Airlines
Air Canada
Website
aircanada.com
Flights from Toronto to Chicago O'Hare
Ave. Duration
1 h 47 min
When
Every day
Estimated price
$140 - $700
Flights from Buffalo to Chicago O'Hare
Ave. Duration
1 h 52 min
When
Every day
Estimated price
$140 - $750
Flights from Toronto to Milwaukee
Ave. Duration
1 h 35 min
When
Every day
Estimated price
$370 - $1,600
United Airlines
Website
united.com
Flights from Toronto to Chicago O'Hare
Ave. Duration
1 h 49 min
When
Every day
Estimated price
$150 - $700
Flights from Buffalo to Chicago O'Hare
Ave. Duration
1 h 52 min
When
Every day
Estimated price
$140 - $750
Flights from Toronto to Milwaukee
Ave. Duration
1 h 35 min
When
Every day
Estimated price
$370 - $1,600
Flights from Toronto to Milwaukee via Chicago O'Hare
Ave. Duration
3 h 45 min
When
Every day
Estimated price
$330 - $1,000
American Airlines
Website
aa.com
Flights from Toronto to Chicago O'Hare
Ave. Duration
2 h 3 min
When
Every day
Estimated price
$130 - $800
Flights from Buffalo to Chicago O'Hare
Ave. Duration
1 h 55 min
When
Every day
Estimated price
$120 - $650
Southwest Airlines
Website
southwest.com
Flights from Buffalo to Chicago Midway
Ave. Duration
1 h 39 min
When
Every day
Estimated price
$160 - $750
Flights from Buffalo to Chicago Midway via Baltimore
Ave. Duration
4 h 1 min
When
Every day
Estimated price
$160 - $750
Delta
Website
delta.com
Flights from Toronto to Chicago O'Hare via Detroit
Ave. Duration
3 h 36 min
When
Every day
Estimated price
$170 - $1,000
Flights from Buffalo to Chicago Midway via Detroit
Ave. Duration
3 h 32 min
When
Every day
Estimated price
$130 - $800
Flights from Buffalo to Chicago O'Hare via Detroit
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$130 - $800
Flights from Toronto to Milwaukee via Detroit
Ave. Duration
3 h 38 min
When
Monday to Friday
Estimated price
$270 - $950
Porter Airlines
Website
flyporter.com
Flights from Toronto Island to Chicago Midway
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$120 - $700
Train operators
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Guelph to Toronto
Ave. Duration
1 h 5 min
Frequency
Hourly
Estimated price
$23 - $65
Website
viarail.ca
Escape
$23 - $35
Economy
$28 - $40
Economy Plus
$45 - $65
Business
$40 - $55
Business Plus/Sleeper
$70 - $110
Train from Guelph to Sarnia
Ave. Duration
3 h 29 min
Frequency
Every 3 hours
Estimated price
$30 - $95
Website
viarail.ca
Escape
$30 - $45
Economy
$45 - $65
Economy Plus
$70 - $95
Business
$65 - $90
Business Plus/Sleeper
$110 - $170
Train from Guelph to London
Ave. Duration
2 h 11 min
Frequency
Hourly
Estimated price
$26 - $75
Website
viarail.ca
Escape
$26 - $40
Economy
$30 - $45
Economy Plus
$50 - $75
Business
$45 - $65
Business Plus/Sleeper
$85 - $120
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Milwaukee Intermodal Station Amtrak to Chicago Union Station Amtrak
Ave. Duration
1 h 29 min
Frequency
Every 4 hours
Estimated price
$25
Website
amtrak.com
Coach Seat
$25
Train from Port Huron Amtrak to Chicago Union Station Amtrak
Ave. Duration
6 h 25 min
Frequency
Once daily
Estimated price
$55 - $150
Website
amtrak.com
Coach Seat
$55 - $80
Flexi Coach Seat
$95 - $140
Business Coach Seat
$100 - $150
Room
$250 - $350
Train from Dearborn Amtrak to Chicago Union Station Amtrak
Ave. Duration
4 h 41 min
Frequency
3 times a day
Estimated price
$45 - $130
Website
amtrak.com
Coach Seat
$45 - $75
Flexi Coach Seat
$85 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Toronto, ON to Buffalo, NY
Ave. Duration
2 h 10 min
Frequency
Every 4 hours
Estimated price
$11 - $21
Schedules at
us.megabus.com
Bus from Detroit, MI to Chicago, IL
Ave. Duration
14 h 5 min
Frequency
4 times a day
Estimated price
$19 - $40
Schedules at
us.megabus.com
Megabus CA
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Toronto, ON to Buffalo, NY
Ave. Duration
1 h 37 min
Frequency
Once daily
Estimated price
$14 - $40
Website
Greyhound.ca
Advanced Purchase
$14 - $21
Online Fare
$16 - $35
Standard Fare
$25 - $40
Refundable
$29 - $45
Bus from Guelph, ON to London, ON
Ave. Duration
2 h 7 min
Frequency
Once daily
Estimated price
$13 - $35
Website
Greyhound.ca
Advanced Purchase
$13 - $20
Online Fare
$15 - $30
Standard Fare
$23 - $35
Refundable
$27 - $40
Bus from London, ON to Chicago, IL
Ave. Duration
8 h 17 min
Frequency
4 times a day
Estimated price
$35 - $95
Website
Greyhound.ca
Advanced Purchase
$35 - $55
Online Fare
$50 - $75
Standard Fare
$65 - $95
Refundable
$70 - $110
Greyhound USA
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from London, On to Dearborn Amtrak, Mi
Ave. Duration
5 h 15 min
Frequency
Hourly
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
Bus from London, On to Detroit, Mi
Ave. Duration
3 h 5 min
Frequency
Hourly
Estimated price
$18 - $45
Website
greyhound.com
Economy
$18 - $27
Flexible
$30 - $45

Want to know more about travelling around United States

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Questions & Answers

The distance between Guelph and Chicago is 630 km. The road distance is 762 km.

The cheapest way to get from Guelph to Chicago is to drive which costs $80 - $120 and takes 8 h 2 min.

The quickest way to get from Guelph to Chicago is to train and fly which takes 5 h 48 min and costs $160 - $550.

No, there is no direct bus from Guelph to Chicago. However, there are services departing from Guelph, ON and arriving at Chicago, IL via London, ON. The journey, including transfers, takes approximately 11 h 24 min.

It takes approximately 6 h 3 min to get from Guelph to Chicago, including transfers.