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There are 10 ways to get from Guelph to Chicago by bus, plane, car, train or night bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus to Toronto, fly to Chicago O'Hare  •  5h 51m

  1. Take the bus from Guelph, ON - 79 Carden Street to Toronto, ON - Pearson International Airport
  2. Fly from Toronto (YYZ) to Chicago O'Hare (ORD) YYZ - ORD

$112 - $381

Cheapest option

Bus, night bus  •  13h

  1. Take the bus from Guelph, ON - 79 Carden Street to London, ON - 101 York St Toronto
  2. Take the night bus from London, On to Chicago Amtrak, Il 5531

$54 - $144

8 alternative options

Drive to Erie, fly to Chicago O'Hare  •  6h 13m

  1. Drive from Guelph to Erie
  2. Fly from Erie (ERI) to Chicago O'Hare (ORD) ERI - ORD

$168 - $842

Train to Billy Bishop Toronto City, fly to Chicago Midway  •  6h 27m

  1. Take the train from Guelph Central GO to Union Station
  2. Fly from Billy Bishop Toronto City (YTZ) to Chicago Midway (MDW) YTZ - MDW

$113 - $443

Bus, bus to Buffalo, fly to Chicago Midway  •  8h 40m

  1. Take the bus from Guelph, ON - 79 Carden Street to Toronto, ON - Pearson International Airport Terminal 1
  2. Take the bus from Toronto, ON - Pearson International Airport to Buffalo Airport, NY
  3. Fly from Buffalo (BUF) to Chicago Midway (MDW) BUF - MDW

$157 - $470

Bus, bus to Buffalo, fly to Chicago O'Hare  •  9h 11m

  1. Take the bus from Guelph, ON - 79 Carden Street to Toronto, ON - Pearson International Airport Terminal 1
  2. Take the bus from Toronto, ON - Pearson International Airport to Buffalo Airport, NY
  3. Fly from Buffalo (BUF) to Chicago O'Hare (ORD) BUF - ORD

$147 - $441

Bus to Toronto, fly to Milwaukee, train  •  8h 4m

  1. Take the bus from Guelph, ON - 79 Carden Street to Toronto, ON - Pearson International Airport
  2. Fly from Toronto (YYZ) to Milwaukee (MKE) YYZ - MKE
  3. Take the train from Milwaukee Intermodal Station to Chicago Union Station

$177 - $507

Train  •  11h 7m

  1. Take the train from Guelph to Sarnia VIA Rail
  2. Take the train from Port Huron Amtrak Station to Chicago Union Station Blue Water

$105 - $247

Bus  •  14h

  1. Take the bus from Guelph, ON - 79 Carden Street to Toronto, ON - Pearson International Airport 5660
  2. Take the bus from Toronto Pearson International Airport to Chicago, IL - 630 West Harrison Street Toronto

$55 - $136

Drive  •  8h 2m

  1. Drive from Guelph to Chicago 476.5 miles

$60 - $95

Questions & Answers

The cheapest way to get from Guelph to Chicago is to drive which costs $80 - $120 and takes 8h 2m.

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The quickest way to get from Guelph to Chicago is to bus and fly which costs $140 - $500 and takes 5h 51m.

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No, there is no direct bus from Guelph to Chicago. However, there are services departing from Guelph, ON - 79 Carden Street and arriving at Chicago, IL - 630 West Harrison Street via Toronto Pearson International Airport. The journey, including transfers, takes approximately 14h.

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The distance between Guelph and Chicago is 630 km. The road distance is 762.3 km.

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The best way to get from Guelph to Chicago without a car is to bus which takes 14h and costs $70 - $180.

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It takes approximately 5h 51m to get from Guelph to Chicago, including transfers.

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Guelph to Chicago bus services, operated by Greyhound Canada, depart from Guelph, ON - 79 Carden Street station.

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The best way to get from Guelph to Chicago is to train which takes 11h 7m and costs $130 - $330. Alternatively, you can bus, which costs $70 - $180 and takes 14h.

Mode details

The quickest flight from Toronto Airport to Chicago O'Hare Airport is the direct flight which takes 1h 48m.

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Guelph to Chicago bus services, operated by Greyhound Canada, arrive at Chicago, IL - 630 West Harrison Street station.

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Map of how to get from Guelph to Chicago.
Launch map view
  • Distance: 393.8 miles
  • Duration: 5h 51m

What companies run services between Guelph, ON, Canada and Chicago, IL, USA?

You can take a train from Guelph to Chicago via Sarnia and Port Huron Amtrak Station in around 11h 7m. Alternatively, you can take a bus from Guelph to Chicago via Toronto, ON - Pearson International Airport and Toronto Pearson International Airport in around 14h.

Airlines
United Airlines
Website
united.com
Flights from Toronto to Chicago O'Hare
Ave. Duration
1h 57m
When
Every day
Estimated price
$150 - $700
Flights from Erie to Chicago O'Hare
Ave. Duration
1h 59m
When
Every day
Estimated price
$170 - $850
Flights from Buffalo to Chicago O'Hare
Ave. Duration
2h 5m
When
Every day
Estimated price
$140 - $750
Flights from Buffalo to Chicago O'Hare via Washington Dulles
Ave. Duration
4h 31m
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$140 - $750
Flights from Toronto to Milwaukee
Ave. Duration
1h 44m
When
Every day
Estimated price
$370 - $1,600
Flights from Toronto to Milwaukee via Chicago O'Hare
Ave. Duration
3h 53m
When
Every day
Estimated price
$340 - $1,200
Air Canada
Website
aircanada.com
Flights from Toronto to Chicago O'Hare
Ave. Duration
1h 52m
When
Every day
Estimated price
$130 - $700
Flights from Buffalo to Chicago O'Hare
Ave. Duration
2h 5m
When
Every day
Estimated price
$140 - $750
Flights from Toronto to Milwaukee
Ave. Duration
1h 44m
When
Every day
Estimated price
$370 - $1,600
American Airlines
Website
aa.com
Flights from Toronto to Chicago O'Hare
Ave. Duration
2h 6m
When
Every day
Estimated price
$130 - $800
Flights from Erie to Chicago O'Hare
Ave. Duration
1h 40m
When
Every day
Estimated price
$160 - $800
Flights from Buffalo to Chicago O'Hare
Ave. Duration
2h 6m
When
Every day
Estimated price
$120 - $650
Flights from Buffalo to Chicago O'Hare via Philadelphia
Ave. Duration
4h 47m
When
Every day
Estimated price
$120 - $650
Flights from Buffalo to Chicago O'Hare via Reagan Washington
Ave. Duration
4h 58m
When
Every day
Estimated price
$120 - $650
Delta
Website
delta.com
Flights from Erie to Chicago O'Hare via Detroit
Ave. Duration
4h 19m
When
Every day
Estimated price
$140 - $800
Flights from Buffalo to Chicago Midway via Detroit
Ave. Duration
4h 5m
When
Monday to Saturday
Estimated price
$130 - $800
Flights from Buffalo to Chicago O'Hare via Detroit
Ave. Duration
4h 12m
When
Every day
Estimated price
$130 - $800
Flights from Toronto to Milwaukee via Detroit
Ave. Duration
4h 6m
When
Every day
Estimated price
$270 - $950
Porter Airlines
Website
flyporter.com
Flights from Billy Bishop Toronto City to Chicago Midway
Ave. Duration
1h 50m
When
Every day
Estimated price
$120 - $700
Southwest Airlines
Website
southwest.com
Flights from Buffalo to Chicago Midway
Ave. Duration
1h 49m
When
Every day
Estimated price
$160 - $750
Flights from Buffalo to Chicago Midway via Baltimore
Ave. Duration
4h 10m
When
Saturday
Estimated price
$160 - $750
Train operators
GO Transit
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Guelph to Toronto
Ave. Duration
1h 5m
Frequency
Twice daily
Estimated price
$35 - $80
Website
viarail.ca
Escape
$16 - $40
Economy
$35 - $55
EconomyPlus
$55 - $80
Business
$50 - $70
Train from Guelph to Sarnia
Ave. Duration
3h 29m
Frequency
Once daily
Estimated price
$45 - $95
Website
viarail.ca
Escape
$27 - $50
Economy
$45 - $70
EconomyPlus
$65 - $95
Business
$70 - $110
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Milwaukee Intermodal Station to Chicago Union Station
Ave. Duration
1h 29m
Frequency
Every 4 hours
Estimated price
$25
Website
amtrak.com
Coach Seat
$25
Train from Port Huron Amtrak Station to Chicago Union Station
Ave. Duration
6h 25m
Frequency
Once daily
Estimated price
$55 - $150
Website
amtrak.com
Coach Seat
$55 - $80
Flexi Coach Seat
$95 - $140
Business Coach Seat
$100 - $150
Room
$250 - $350
Bus operators
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Guelph, ON - 79 Carden Street to Toronto, ON - Pearson International Airport
Ave. Duration
1h 15m
Frequency
Twice daily
Estimated price
$10 - $27
Website
Greyhound.ca
Advanced Purchase
$10 - $15
Online Fare
$10 - $24
Standard Fare
$18 - $27
Refundable
$21 - $35
Bus from Guelph, ON - 79 Carden Street to Toronto, ON - Pearson International Airport Terminal 1
Ave. Duration
1h 15m
Frequency
5 times a week
Estimated price
$10 - $26
Website
Greyhound.ca
Advanced Purchase
$10 - $15
Online Fare
$10 - $23
Standard Fare
$18 - $26
Refundable
$21 - $30
Bus from Toronto, ON - Pearson International Airport to Buffalo Airport, NY
Ave. Duration
3h 5m
Frequency
Once daily
Estimated price
$15 - $40
Website
Greyhound.ca
Advanced Purchase
$15 - $22
Online Fare
$17 - $35
Standard Fare
$26 - $40
Refundable
$30 - $45
Bus from Toronto Pearson International Airport to Chicago, IL - 630 West Harrison Street
Ave. Duration
11h 45m
Frequency
Once daily
Estimated price
$45 - $110
Website
Greyhound.ca
Advanced Purchase
$45 - $65
Online Fare
$60 - $90
Standard Fare
$75 - $110
Refundable
$85 - $120
Bus from Guelph, ON - 79 Carden Street to London, ON - 101 York St
Ave. Duration
2h 10m
Frequency
Once daily
Estimated price
$13 - $35
Website
Greyhound.ca
Advanced Purchase
$13 - $20
Online Fare
$15 - $29
Standard Fare
$23 - $35
Refundable
$27 - $40
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Night bus from London, On to Chicago Amtrak, Il
Ave. Duration
9h 50m
Frequency
Once daily
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Chicago is 1h behind Guelph. It is currently 2:43 AM in Guelph and 1:43 AM in Chicago.

Yes, the driving distance between Guelph to Chicago is 762 km. It takes approximately 8h 2m to drive from Guelph to Chicago.

Get driving directions

United Airlines, American Airlines and Air Canada offer flights from Toronto Airport to Chicago O'Hare Airport.

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There are 763+ hotels available in Chicago. Prices start at $75 USD per night.

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