There are 11 ways to get from Guelph to Chicago by train, plane, car or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train to Billy Bishop Toronto City, fly to Chicago Midway  •  5 h 47 min

  1. Take the train from Guelph to Toronto
  2. Fly from Billy Bishop Toronto City (YTZ) to Chicago Midway (MDW) YTZ - MDW

$128 - $430

Cheapest option

Bus  •  11 h 24 min

  1. Take the bus from Guelph, ON to London, ON 5503 / 5502 / ...
  2. Take the bus from London, ON to Chicago, IL 5515 / ...

$48 - $128

9 alternative options

Train to Toronto, fly to Chicago O'Hare  •  6 h 8 min

  1. Take the train from Guelph to Toronto
  2. Fly from Toronto (YYZ) to Chicago O'Hare (ORD) YYZ - ORD

$129 - $428

Drive to Erie, fly to Chicago O'Hare  •  6 h 14 min

  1. Drive from Guelph to Erie
  2. Fly from Erie (ERI) to Chicago O'Hare (ORD) ERI - ORD

$168 - $842

Train, bus to Buffalo, fly to Chicago Midway  •  8 h 7 min

  1. Take the train from Guelph to Toronto
  2. Take the bus from Toronto, ON to Buffalo, NY
  3. Fly from Buffalo (BUF) to Chicago Midway (MDW) BUF - MDW

$177 - $508

Train, bus to Buffalo, fly to Chicago O'Hare  •  8 h 27 min

  1. Take the train from Guelph to Toronto
  2. Take the bus from Toronto, ON to Buffalo, NY
  3. Fly from Buffalo (BUF) to Chicago O'Hare (ORD) BUF - ORD

$167 - $479

Train to Toronto, fly to Milwaukee, train  •  8 h 17 min

  1. Take the train from Guelph to Toronto
  2. Fly from Toronto (YYZ) to Milwaukee (MKE) YYZ - MKE
  3. Take the train from Milwaukee Intermodal Station to Chicago Union Station

$194 - $554

Train  •  10 h 35 min

  1. Take the train from Guelph to London
  2. Take the train from London to Windsor
  3. Take the train from Detroit Amtrak to Chicago Union Station

$106 - $289

Train, bus, Megabus  •  13 h 1 min

  1. Take the train from Guelph to London
  2. Take the bus from London, On to Detroit, Mi
  3. Take the Megabus from Downtown Detroit to Chicago

$74 - $159

Train, bus  •  13 h 59 min

  1. Take the train from Guelph to London
  2. Take the bus from London, On to Dearborn Amtrak, Mi
  3. Take the train from Dearborn Amtrak to Chicago Union Station

$91 - $252

Drive  •  8 h 2 min

  1. Drive from Guelph to Chicago 476.5 miles

$60 - $95

Questions & Answers

The cheapest way to get from Guelph to Chicago is to drive which costs $80 - $120 and takes 8 h 2 min.

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The quickest way to get from Guelph to Chicago is to train and fly which costs $160 - $600 and takes 5 h 47 min.

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No, there is no direct bus from Guelph to Chicago. However, there are services departing from Guelph, ON and arriving at Chicago, IL via London, ON. The journey, including transfers, takes approximately 11 h 24 min.

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The distance between Guelph and Chicago is 630 km. The road distance is 762.3 km.

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The best way to get from Guelph to Chicago without a car is to bus which takes 11 h 24 min and costs $60 - $170.

More details

It takes approximately 5 h 47 min to get from Guelph to Chicago, including transfers.

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Guelph to Chicago bus services, operated by Greyhound Canada, depart from Guelph, ON station.

More details

The best way to get from Guelph to Chicago is to train which takes 10 h 35 min and costs $130 - $380. Alternatively, you can bus, which costs $60 - $170 and takes 11 h 24 min.

Mode details

The quickest flight from Billy Bishop Toronto City Airport to Chicago Midway Airport is the direct flight which takes 1 h 47 min.

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Guelph to Chicago bus services, operated by Greyhound Canada, arrive at Chicago, IL station.

More details

Chicago is 1 h behind Guelph. It is currently 11:14 PM in Guelph and 10:14 PM in Chicago.

Yes, the driving distance between Guelph to Chicago is 762 km. It takes approximately 8 h 2 min to drive from Guelph to Chicago.

Get driving directions

Map of how to get from Guelph to Chicago.
Launch map view
  • Distance: 393.8 miles
  • Duration: 5 h 47 min

What companies run services between Guelph, ON, Canada and Chicago, IL, USA?

You can take a train from Guelph to Chicago via London, Windsor, and Detroit Amtrak in around 10 h 35 min. Alternatively, you can take a bus from Guelph to Chicago via London, ON in around 11 h 24 min.

Airlines
United Airlines
Website
united.com
Flights from Toronto to Chicago O'Hare
Ave. Duration
1 h 53 min
When
Every day
Estimated price
$140 - $700
Flights from Erie to Chicago O'Hare
Ave. Duration
1 h 41 min
When
Every day
Estimated price
$170 - $850
Flights from Buffalo to Chicago O'Hare
Ave. Duration
1 h 48 min
When
Every day
Estimated price
$140 - $750
Flights from Buffalo to Chicago O'Hare via Washington Dulles
Ave. Duration
4 h 8 min
When
Every day
Estimated price
$140 - $750
Flights from Toronto to Milwaukee
Ave. Duration
1 h 35 min
When
Every day
Estimated price
$370 - $1,600
Flights from Toronto to Milwaukee via Chicago O'Hare
Ave. Duration
4 h 10 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$330 - $1,000
Air Canada
Website
aircanada.com
Flights from Toronto to Chicago O'Hare
Ave. Duration
1 h 50 min
When
Every day
Estimated price
$130 - $700
Flights from Buffalo to Chicago O'Hare
Ave. Duration
1 h 48 min
When
Every day
Estimated price
$140 - $750
Flights from Toronto to Milwaukee
Ave. Duration
1 h 35 min
When
Every day
Estimated price
$370 - $1,600
Delta
Website
delta.com
Flights from Toronto to Chicago O'Hare via Detroit
Ave. Duration
3 h 33 min
When
Every day
Estimated price
$170 - $1,000
Flights from Erie to Chicago O'Hare via Detroit
Ave. Duration
3 h 30 min
When
Every day
Estimated price
$140 - $800
Flights from Buffalo to Chicago Midway via Detroit
Ave. Duration
3 h 31 min
When
Every day
Estimated price
$130 - $800
Flights from Buffalo to Chicago O'Hare via Detroit
Ave. Duration
3 h 43 min
When
Every day
Estimated price
$130 - $800
Flights from Toronto to Milwaukee via Detroit
Ave. Duration
3 h 16 min
When
Every day
Estimated price
$270 - $950
Southwest Airlines
Website
southwest.com
Flights from Buffalo to Chicago Midway
Ave. Duration
1 h 38 min
When
Every day
Estimated price
$160 - $750
Flights from Buffalo to Chicago Midway via Baltimore
Ave. Duration
4 h 3 min
When
Saturday and Sunday
Estimated price
$160 - $750
American Airlines
Website
aa.com
Flights from Toronto to Chicago O'Hare
Ave. Duration
1 h 58 min
When
Every day
Estimated price
$130 - $800
Flights from Buffalo to Chicago O'Hare
Ave. Duration
1 h 55 min
When
Every day
Estimated price
$120 - $650
Flights from Toronto to Milwaukee via Chicago O'Hare
Ave. Duration
4 h 5 min
When
Every day
Estimated price
$260 - $750
Porter Airlines
Website
flyporter.com
Flights from Billy Bishop Toronto City to Chicago Midway
Ave. Duration
1 h 47 min
When
Every day
Estimated price
$120 - $700
Train operators
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Guelph to Toronto
Ave. Duration
1 h 5 min
Frequency
Hourly
Estimated price
$23 - $65
Website
viarail.ca
Escape
$23 - $35
Economy
$28 - $40
Economy Plus
$45 - $65
Business
$35 - $55
Business Plus/Sleeper
$70 - $100
Train from Guelph to London
Ave. Duration
2 h 11 min
Frequency
Hourly
Estimated price
$25 - $75
Website
viarail.ca
Escape
$25 - $35
Economy
$30 - $45
Economy Plus
$50 - $75
Business
$45 - $65
Business Plus/Sleeper
$85 - $120
Train from London to Windsor
Ave. Duration
1 h 54 min
Frequency
Every 30 minutes
Estimated price
$29 - $85
Website
viarail.ca
Escape
$29 - $40
Economy
$40 - $55
Economy Plus
$60 - $85
Business
$55 - $80
Business Plus/Sleeper
$100 - $150
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Milwaukee Intermodal Station to Chicago Union Station
Ave. Duration
1 h 29 min
Frequency
Every 4 hours
Estimated price
$25
Website
amtrak.com
Coach Seat
$25
Train from Detroit Amtrak to Chicago Union Station
Ave. Duration
4 h 59 min
Frequency
3 times a day
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Train from Dearborn Amtrak to Chicago Union Station
Ave. Duration
4 h 41 min
Frequency
3 times a day
Estimated price
$45 - $130
Website
amtrak.com
Coach Seat
$45 - $75
Flexi Coach Seat
$85 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Toronto, ON to Buffalo, NY
Ave. Duration
2 h 16 min
Frequency
4 times a day
Estimated price
$11 - $21
Book at
megabus.com
Bus from Downtown Detroit to Chicago
Ave. Duration
5 h 45 min
Frequency
Twice daily
Estimated price
$28 - $40
Book at
megabus.com
Megabus Canada
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Toronto, ON to Buffalo, NY
Ave. Duration
1 h 37 min
Frequency
Once daily
Estimated price
$14 - $40
Website
Greyhound.ca
Advanced Purchase
$14 - $21
Online Fare
$16 - $35
Standard Fare
$25 - $40
Refundable
$29 - $45
Bus from Guelph, ON to London, ON
Ave. Duration
2 h 7 min
Frequency
Once daily
Estimated price
$13 - $35
Website
Greyhound.ca
Advanced Purchase
$13 - $19
Online Fare
$14 - $29
Standard Fare
$23 - $35
Refundable
$27 - $40
Bus from London, ON to Chicago, IL
Ave. Duration
8 h 17 min
Frequency
4 times a day
Estimated price
$35 - $95
Website
Greyhound.ca
Advanced Purchase
$35 - $55
Online Fare
$45 - $75
Standard Fare
$60 - $95
Refundable
$70 - $100
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from London, On to Detroit, Mi
Ave. Duration
3 h 5 min
Frequency
Hourly
Estimated price
$18 - $45
Website
greyhound.com
Economy
$18 - $27
Flexible
$30 - $45
Bus from London, On to Dearborn Amtrak, Mi
Ave. Duration
5 h 15 min
Frequency
Hourly
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50

Want to know more about travelling around United States

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