Rome2Rio

Genoa to Sicily buses

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Trip Overview

The average bus between Genoa and Sicily takes 22h 4m and the fastest bus takes 21h 22m. The bus service runs several times per day from Genoa to Sicily. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 4m
Duration
1,505 km
Distance
€156
Average price
Twice daily
Frequency

Genoa to Sicily bus times

Buses run twice daily between Genoa and Sicily. The earliest departure is at 12:45 PM in the afternoon, and the last departure from Genoa is at 6:20 PM which arrives into Sicily at 3:43 PM. All services require a transfer at Florence Villa Constanza Bus Station and take an average of 22h 4m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.22h 38m • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.22h 38m • 2 changes
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    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.21h 23m • 2 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.22h 42m • 2 changes
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    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.21h 22m • 2 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.22h 38m • 2 changes
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    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.21h 23m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.22h 38m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.21h 23m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.22h 38m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.21h 23m • 2 changes

Frequently asked questions

Want to know about travelling from Genoa to Sicily? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Genoa to Sicily.ExpandLaunch map view
  • Distance: 1,505.1 km
  • Duration: 22h 4m

What companies run services between Genoa, Italy and Sicily, Italy?

You can take a bus from Genoa to Piazza Boiardo via Florence Villa Constanza Bus Station, Palermo, and Stazione Centrale Pensilina Esterna in around 21h 7m.

Operators