The average bus between Frederick and Rochester takes 13h 32m and the fastest bus takes 11h 10m. There is at least one bus per day from Frederick to Rochester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Frederick and Rochester. The earliest departure is at 11:30 AM in the morning, and the last departure from Frederick is at 7:30 PM which arrives into Rochester at 6:40 AM. All services require a transfer at Baltimore Downtown Bus Station and take an average of 13h 32m. The schedules shown below are for the next available departures.
Arrives next day


15h 55m • 2 changes
Arrives next day


11h 10m • 2 changes
Arrives next day


15h 55m • 2 changes
Arrives next day


11h 10m • 2 changes
Want to know about travelling from Frederick to Rochester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Frederick to Rochester. However, there are services departing from Frederick station and arriving at Rochester station via Baltimore Downtown Bus Terminal, Baltimore, MD. The journey, including transfers, takes approximately 13h 32m.
Frederick to Rochester bus services, operated by BayRunner Shuttle, depart from Frederick Bayrunner Office station.
Frederick to Rochester bus services, operated by BayRunner Shuttle, arrive at Rochester Bus Stop station.
Book your Frederick to Rochester bus tickets online with BayRunner Shuttle, Greyhound USA and Flixbus USA.
The distance between Frederick and Rochester is 416.3 km. The road distance is 892 km.
You can take a bus from Frederick Bayrunner Office to Rochester Bus Stop via Baltimore Downtown Bus Station and Newark Penn Station in around 12h 20m.