The average bus between East Harlem and Boston takes 6h 21m and the fastest bus takes 4h 33m. The bus service runs several times per day from East Harlem to Boston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between East Harlem and Boston. The earliest departure is at 9:50 AM in the morning, and the last departure from East Harlem is at 7:47 PM which arrives into Boston at 5:10 AM. All services require a transfer at 34 St-Penn Station and take an average of 6h 21m. The schedules shown below are for the next available departures.

7h 24m • 1 change

5h 11m • 1 change
Arrives next day

9h 22m • 1 change

4h 44m • 1 change

7h 24m • 1 change

5h 11m • 1 change
Arrives next day

9h 22m • 1 change

4h 44m • 1 change

7h 24m • 1 change

5h 11m • 1 change
Arrives next day

9h 22m • 1 change

4h 44m • 1 change

7h 24m • 1 change

5h 11m • 1 change

4h 33m • 1 change
Want to know about travelling from East Harlem to Boston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from East Harlem to Boston. However, there are services departing from East Harlem station and arriving at Boston station via Boston. The journey, including transfers, takes approximately 6h 21m.
East Harlem to Boston bus services, operated by MTA Bus Company, depart from New York Midtown station.
East Harlem to Boston bus services, operated by MTA Bus Company, arrive at Boston station.
The distance between East Harlem and Boston is 296.2 km. The road distance is 350 km.
Flixbus USA operates a bus from New York Midtown to Boston hourly. Tickets cost $30–55 and the journey takes 4h 20m.