The average bus between Como and Lyon takes 9h 48m and the fastest bus takes 8h. The bus service runs several times per day from Como to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Como and Lyon. The earliest departure is at 6:25 AM in the morning, and the last departure from Como is at 9:30 PM which arrives into Lyon at 12:00 PM. All services require a transfer, and take on average 9h 48m. The schedules shown below are for the next available departures.

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Arrives next day

14h 30m • 1 change

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11h 5m • 1 change
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14h 30m • 1 change

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11h 5m • 1 change
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10h • 1 change

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Arrives next day

14h 30m • 1 change
Want to know about travelling from Como to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Como to Lyon. However, there are services departing from Como station and arriving at Lyon station via Milan. The journey, including transfers, takes approximately 9h 48m.
Como to Lyon bus services, operated by FlixBus, depart from Como station.
Como to Lyon bus services, operated by FlixBus, arrive at Lyon - Gerland Bus Station.
Book your Como to Lyon bus tickets online with FlixBus and BlaBlaCar Bus.
The distance between Como and Lyon is 328.6 km. The road distance is 488 km.
You can take a bus from Como to Lyon - Gerland Bus Station via Milano, Autostazione Lampugnano in around 8h 5m.