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Chicago to Mesa buses

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Trip Overview

The bus between Chicago and Mesa takes 3d 5h. The bus runs, on average, 3 times per week from Chicago to Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3d 5h
Duration
2,147 mi
Distance
$476
Average price
3 times a week
Frequency

Chicago to Mesa bus times

Buses run 3 times a week between Chicago and Mesa. The service departs Chicago at 12:25 PM in the afternoon, which arrives into Mesa at 17:50:00. All services require a transfer at Denver Union Station and take an average of 3d 5h. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAGreyhound USAFlixbus USAValley Metro3d 6h • 4 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAGreyhound USAFlixbus USAValley Metro3d 5h • 4 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAGreyhound USAFlixbus USAValley Metro3d 5h • 4 changes

Frequently asked questions

Want to know about travelling from Chicago to Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago to Mesa.ExpandLaunch map view
  • Distance: 2,146.9 mi
  • Duration: 3d 5h

What companies run services between Chicago, IL, USA and Mesa, AZ, USA?

You can take a bus from Chicago Bus Station to University Dr & Mesa Dr via Denver Union Station, El Paso Bus Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, Tempe, and University Dr & Rural Rd in around 2d.

Operators