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How to get fromChicago to Mesaby plane, train, bus, bus (Greyhound, Flixbus) or car

Find Transport to Mesa

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There are 7 ways to get from Chicago to Mesa by plane, train, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago O'Hare International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Phoenix (PHX)plane plane ORD - PHX
    6h 38m
    $224–657
  2. Fly from Chicago Midway International Airport

    cheapest
    1. Fly from Chicago Midway International Airport (MDW) to Phoenix (PHX)plane plane MDW - PHX
    6h 23m
    $174–807
  3. Train, bus via Flagstaff

    1. Take the train from Chicago Union Station to Flagstafftrain train Southwest Chief
    2. Take the bus from Flagstaff Train Station to Phoenix Sky Harbor Airport/44th Street Sky Train Stationbus bus FlixBus 2047
    36h
    $178–1,083
  4. Bus

    1. Take the bus from Chicago Bus Station to Denver Union Stationbus bus
    2. Take the bus from Denver Union Station to Las Vegas BusTerminalbus bus
    3. Take the bus from Las Vegas Strip to Tempebus bus
    47h 15m
    $204–552
  5. Drive 1,688.8 mi

    1. Drive from Chicago to Mesacar car 1,688.8 mi
    29h 41m
    $309–446
  6. Train to General Mitchell International Airport, fly

    1. Take the train from Chicago Union Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to Phoenix (PHX)plane plane MKE - PHX
    7h 50m
    $256–1,220
  7. Train, bus

    1. Take the train from Chicago Union Station to Tucson Amtrak Stationtrain train Texas Eagle
    2. Take the bus from Tucson Downtown to Tempebus bus FlixBus 2047 / ...
    2d 11h
    $207–1,382

Chicago to Mesa by train, bus, and tram

Calendar9Weekly Services
Duration36hAverage Duration
Ticket$178Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Mesa, AZ, USA?

American Airlines, Frontier Airlines, and two other airlines fly from Chicago O'Hare International Airport (ORD) to Phoenix (PHX) hourly. Alternatively, you can take a bus from Chicago Bus Station to University Dr & Mesa Dr via Denver Union Station, Las Vegas BusTerminal, Las Vegas Strip, Tempe, and University Dr & Rural Rd in around 47h 15m.

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Want to know more about travelling around United States

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