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Chicago to Gainesville buses

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Trip Overview

The average bus between Chicago and Gainesville takes 23h 47m and the fastest bus takes 22h 5m. The bus service runs several times per day from Chicago to Gainesville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

23h 47m
Duration
1,049 mi
Distance
$213
Average price
3 times a day
Frequency

Chicago to Gainesville bus times

Buses run 3 times a day between Chicago and Gainesville. The earliest departure is at 6:10 AM in the morning, and the last departure from Chicago is at 10:50 PM which arrives into Gainesville at 11:15 PM. All services require a transfer, and take on average 23h 47m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAFlixbus USA22h 5m • 1 change
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    Arrives next day

    Flixbus USAFlixbus USA23h 55m • 1 change
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    Arrives next day

    Greyhound USAFlixbus USA23h 25m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USA22h 5m • 1 change
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    Arrives next day

    Flixbus USAFlixbus USA23h 55m • 1 change
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    Arrives next day

    Greyhound USAFlixbus USA23h 25m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USA22h 5m • 1 change
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    Arrives next day

    Flixbus USAFlixbus USA23h 55m • 1 change
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    Arrives next day

    Greyhound USAFlixbus USA23h 25m • 1 change

Departing Sunday, November 15, 2026

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    Arrives next day

    Greyhound USAFlixbus USA22h 5m • 1 change
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    Arrives next day

    Flixbus USAFlixbus USA23h 55m • 1 change
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    Arrives next day

    Greyhound USAFlixbus USA23h 25m • 1 change

Departing Monday, November 16, 2026

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    Arrives next day

    Greyhound USAFlixbus USA22h 5m • 1 change
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    Arrives next day

    Flixbus USAFlixbus USA23h 55m • 1 change
  •  → 

    Arrives next day

    Greyhound USAFlixbus USA23h 25m • 1 change

Departing Tuesday, November 17, 2026

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    Arrives next day

    Greyhound USAFlixbus USA22h 5m • 1 change
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    Arrives next day

    Greyhound USAFlixbus USA27h 10m • 1 change

Frequently asked questions

Want to know about travelling from Chicago to Gainesville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago to Gainesville.ExpandLaunch map view
  • Distance: 1,049.2 mi
  • Duration: 23h 47m

What companies run services between Chicago, IL, USA and Gainesville, FL, USA?

You can take a bus from Chicago Bus Station to Gainesville via Atlanta Bus Station in around 22h 15m.

Operators