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Chicago to Estero buses

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Trip Overview

The average bus between Chicago and Estero takes 42h 58m and the fastest bus takes 42h 49m. The bus runs, on average, 5 times per week from Chicago to Estero. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

42h 58m
Duration
1,385 mi
Distance
$285
Average price
5 times a week
Frequency

Chicago to Estero bus times

Buses run 5 times a week between Chicago and Estero. The service departs Chicago at 10:50 PM at night, which arrives into Estero at 18:39:07. All services require a transfer at Atlanta Bus Station and take an average of 42h 58m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USALee County TransitLee County Transit42h 49m • 4 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USALee County TransitLee County Transit42h 49m • 4 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USALee County TransitLee County Transit42h 49m • 4 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USALee County TransitLee County Transit43h 33m • 4 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USALee County TransitLee County Transit42h 49m • 4 changes

Frequently asked questions

Want to know about travelling from Chicago to Estero? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago to Estero.ExpandLaunch map view
  • Distance: 1,385.4 mi
  • Duration: 42h 58m

What companies run services between Chicago, IL, USA and Estero, FL, USA?

You can take a bus from Chicago Bus Station to S Tamiami Trl @ Lychee Ln via Atlanta Bus Station, Tampa Bus Station, Rosa Parks Transportation Ctr, and South Fort Myers Transfer/P&R in around 32h 5m.

Operators