Rome2Rio

Charlottesville to Florida Keys buses

Find Transport to Florida Keys

View schedule

Trip Overview

The average bus between Charlottesville and Florida Keys takes 2d 17h and the fastest bus takes 44h 45m. The bus runs, on average, 2 times per week from Charlottesville to Florida Keys. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 17h
Duration
1,207 mi
Distance
$220
Average price
Twice a week
Frequency

Charlottesville to Florida Keys bus times

Buses run twice a week between Charlottesville and Florida Keys. The earliest departure is at 3:30 PM in the afternoon, and the last departure from Charlottesville is at 10:00 PM which arrives into Florida Keys at 12:15 PM. All services require a transfer at W Main St at 8th St NW and take an average of 2d 17h. The schedules shown below are for the next available departures.

Departing Friday, October 9, 2026

  •  → 

    Arrives +2 days

    Charlottesville Area TransitAmtrakFlixbus USAGreyhound USAKey West Transit44h 45m • 4 changes

Departing Saturday, October 10, 2026

  •  → 

    Arrives +4 days

    Charlottesville Area TransitAmtrakFlixbus USAGreyhound USAKey West Transit3d 14h • 4 changes

Frequently asked questions

Want to know about travelling from Charlottesville to Florida Keys? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Charlottesville to Florida Keys.ExpandLaunch map view
  • Distance: 1,206.9 mi
  • Duration: 2d 17h

What companies run services between Charlottesville, VA, USA and Florida Keys, FL, USA?

You can take a bus from Downtown Transit Station to Florida Keys via W Main St at 8th St NW, Charlottesville Amtrak Station, Richmond, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 29h 40m.

Operators