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Memphis to Florida Keys buses

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Trip Overview

The average bus between Memphis and Florida Keys takes 41h 20m and the fastest bus takes 40h 56m. The bus runs, on average, 5 times per week from Memphis to Florida Keys. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

41h 20m
Duration
1,219 mi
Distance
$262
Average price
5 times a week
Frequency

Memphis to Florida Keys bus times

Buses run 5 times a week between Memphis and Florida Keys. The earliest departure is at 4:17 PM in the afternoon, and the last departure from Memphis is at 6:18 PM which arrives into Florida Keys at 12:15 PM. All services require a transfer at Memphis Bus Station and take an average of 41h 20m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    MATA TransitGreyhound USAGreyhound USAGreyhound USAKey West Transit40h 56m • 4 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    MATA TransitGreyhound USAGreyhound USAGreyhound USAKey West Transit40h 56m • 4 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    MATA TransitGreyhound USAGreyhound USAGreyhound USAKey West Transit40h 56m • 4 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    MATA TransitGreyhound USAGreyhound USAGreyhound USAKey West Transit40h 56m • 4 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    MATA TransitGreyhound USAGreyhound USAGreyhound USAKey West Transit42h 57m • 4 changes

Frequently asked questions

Want to know about travelling from Memphis to Florida Keys? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Memphis to Florida Keys.ExpandLaunch map view
  • Distance: 1,218.7 mi
  • Duration: 41h 20m

What companies run services between Memphis, TN, USA and Florida Keys, FL, USA?

You can take a bus from 2ND STREET at ADAMS AVENUE to Florida Keys via Memphis Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 29h 51m.

Operators