The average bus between Charlotte and Ithaca takes 21h 18m and the fastest bus takes 18h 26m. The bus service runs several times per day from Charlotte to Ithaca. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Charlotte and Ithaca. The earliest departure is at 1:10 AM at night, and the last departure from Charlotte is at 11:59 PM which arrives into Ithaca at 6:25 PM. All services require a transfer, and take on average 21h 18m. The schedules shown below are for the next available departures.

20h 35m • 1 change
Arrives next day

26h 20m • 1 change
Arrives next day

18h 26m • 1 change
Arrives next day

26h 20m • 1 change
Arrives next day

18h 26m • 1 change
Arrives next day

23h 55m • 1 change
Arrives next day

18h 26m • 1 change
Arrives next day

23h 55m • 1 change
Arrives next day

18h 26m • 1 change

20h 35m • 1 change
Arrives next day

26h 20m • 1 change
Arrives next day

18h 26m • 1 change
Want to know about travelling from Charlotte to Ithaca? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Charlotte to Ithaca. However, there are services departing from Charlotte station and arriving at Ithaca station via New York Midtown. The journey, including transfers, takes approximately 21h 18m.
Charlotte to Ithaca bus services, operated by Flixbus USA, depart from Charlotte Bus Station.
Charlotte to Ithaca bus services, operated by Flixbus USA, arrive at Ithaca station.
Book your Charlotte to Ithaca bus tickets online with Flixbus USA.
The distance between Charlotte and Ithaca is 885.7 km. The road distance is 1,468 km.
You can take a bus from Charlotte Bus Station to Ithaca via New York Midtown in around 18h 26m.